Poulsen MH - Search Results

1

Human P2X7 receptor variants Gly150Arg and Arg276His polymorphisms have differential effects on risk association and cellular functions in pancreatic cancer.

Magni L, Yu H, Christensen NM, Poulsen MH, Frueh A, Deshar G, Johansen AZ, Johansen JS, Pless SA, Jørgensen NR, Novak I. Magni L, et al. Among authors: poulsen mh. Cancer Cell Int. 2024 Apr 25;24(1):148. doi: 10.1186/s12935-024-03339-9. Cancer Cell Int. 2024. PMID: 38664691 Free PMC article.

2

P2X2 receptor subunit interfaces are missense variant hotspots, where mutations tend to increase apparent ATP affinity.

Gasparri F, Sarkar D, Bielickaite S, Poulsen MH, Hauser AS, Pless SA. Gasparri F, et al. Among authors: poulsen mh. Br J Pharmacol. 2022 Jul;179(14):3859-3874. doi: 10.1111/bph.15830. Epub 2022 Mar 29. Br J Pharmacol. 2022. PMID: 35285517 Free PMC article.

3

Chemical modification of proteins by insertion of synthetic peptides using tandem protein trans-splicing.

Khoo KK, Galleano I, Gasparri F, Wieneke R, Harms H, Poulsen MH, Chua HC, Wulf M, Tampé R, Pless SA. Khoo KK, et al. Among authors: poulsen mh. Nat Commun. 2020 May 8;11(1):2284. doi: 10.1038/s41467-020-16208-6. Nat Commun. 2020. PMID: 32385250 Free PMC article.

4

Controlling Ca²⁺ Permeable α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Photochromic Ion Channel Blockers.

Nørager NG, Poulsen MH, Strømgaard K. Nørager NG, et al. Among authors: poulsen mh. J Med Chem. 2018 Sep 13;61(17):8048-8053. doi: 10.1021/acs.jmedchem.8b00756. Epub 2018 Aug 31. J Med Chem. 2018. PMID: 30125106

5

Structure-activity relationship studies of N-methylated and N-hydroxylated spider polyamine toxins as inhibitors of ionotropic glutamate receptors.

Nørager NG, Poulsen MH, Jensen AG, Jeppesen NS, Kristensen AS, Strømgaard K. Nørager NG, et al. Among authors: poulsen mh. J Med Chem. 2014 Jun 12;57(11):4940-9. doi: 10.1021/jm5004705. Epub 2014 May 29. J Med Chem. 2014. PMID: 24824658

6

Binding of ArgTX-636 in the NMDA receptor ion channel.

Poulsen MH, Andersen J, Christensen R, Hansen KB, Traynelis SF, Strømgaard K, Kristensen AS. Poulsen MH, et al. J Mol Biol. 2015 Jan 16;427(1):176-89. doi: 10.1016/j.jmb.2014.05.017. Epub 2014 May 24. J Mol Biol. 2015. PMID: 24862283 Free PMC article.

7

Structure-activity relationship study of spider polyamine toxins as inhibitors of ionotropic glutamate receptors.

Xiong XF, Poulsen MH, Hussein RA, Nørager NG, Strømgaard K. Xiong XF, et al. Among authors: poulsen mh. ChemMedChem. 2014 Dec;9(12):2661-70. doi: 10.1002/cmdc.201402278. Epub 2014 Sep 29. ChemMedChem. 2014. PMID: 25267300

8

General synthesis of β-alanine-containing spider polyamine toxins and discovery of nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptors.

Lucas S, Poulsen MH, Nørager NG, Barslund AF, Bach TB, Kristensen AS, Strømgaard K. Lucas S, et al. Among authors: poulsen mh. J Med Chem. 2012 Nov 26;55(22):10297-301. doi: 10.1021/jm301255m. Epub 2012 Nov 6. J Med Chem. 2012. PMID: 23092360

9

Inhibition of AMPA receptors by polyamine toxins is regulated by agonist efficacy and stargazin.

Poulsen MH, Lucas S, Strømgaard K, Kristensen AS. Poulsen MH, et al. Neurochem Res. 2014 Oct;39(10):1906-13. doi: 10.1007/s11064-014-1258-6. Epub 2014 Feb 22. Neurochem Res. 2014. PMID: 24557991

10

Solid-phase synthesis and biological evaluation of Joro spider toxin-4 from Nephila clavata.

Barslund AF, Poulsen MH, Bach TB, Lucas S, Kristensen AS, Strømgaard K. Barslund AF, et al. Among authors: poulsen mh. J Nat Prod. 2011 Mar 25;74(3):483-6. doi: 10.1021/np100746w. Epub 2010 Dec 28. J Nat Prod. 2011. PMID: 21188966

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