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Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration.
Paumier KL, Luk KC, Manfredsson FP, Kanaan NM, Lipton JW, Collier TJ, Steece-Collier K, Kemp CJ, Celano S, Schulz E, Sandoval IM, Fleming S, Dirr E, Polinski NK, Trojanowski JQ, Lee VM, Sortwell CE. Paumier KL, et al. Among authors: luk kc. Neurobiol Dis. 2015 Oct;82:185-199. doi: 10.1016/j.nbd.2015.06.003. Epub 2015 Jun 17. Neurobiol Dis. 2015. PMID: 26093169 Free PMC article.
Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology.
Manfredsson FP, Luk KC, Benskey MJ, Gezer A, Garcia J, Kuhn NC, Sandoval IM, Patterson JR, O'Mara A, Yonkers R, Kordower JH. Manfredsson FP, et al. Among authors: luk kc. Neurobiol Dis. 2018 Apr;112:106-118. doi: 10.1016/j.nbd.2018.01.008. Epub 2018 Jan 16. Neurobiol Dis. 2018. PMID: 29341898 Free PMC article.
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
Duffy MF, Collier TJ, Patterson JR, Kemp CJ, Luk KC, Tansey MG, Paumier KL, Kanaan NM, Fischer DL, Polinski NK, Barth OL, Howe JW, Vaikath NN, Majbour NK, El-Agnaf OMA, Sortwell CE. Duffy MF, et al. Among authors: luk kc. J Neuroinflammation. 2018 May 1;15(1):129. doi: 10.1186/s12974-018-1171-z. J Neuroinflammation. 2018. PMID: 29716614 Free PMC article.
Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
Duffy MF, Collier TJ, Patterson JR, Kemp CJ, Luk KC, Tansey MG, Paumier KL, Kanaan NM, Fischer DL, Polinski NK, Barth OL, Howe JW, Vaikath NN, Majbour NK, El-Agnaf OMA, Sortwell CE. Duffy MF, et al. Among authors: luk kc. J Neuroinflammation. 2018 May 29;15(1):169. doi: 10.1186/s12974-018-1202-9. J Neuroinflammation. 2018. PMID: 29843738 Free PMC article.
174 results