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Accelerating Pharmaceutical Process Development with an Acoustic Droplet Ejection-Multiple Reaction Monitoring-Mass Spectrometry Workflow.
Hu H, Singh AN, Lehnherr D, Mdluli V, Chun SW, Makarewicz AM, Gouker JR, Ukaegbu O, Li S, Wen X, McLaren DG, Velasquez JE, Moore JC, Galanie S, Appiah-Amponsah E, Regalado EL. Hu H, et al. Among authors: regalado el. Anal Chem. 2024 Jan 23;96(3):1138-1146. doi: 10.1021/acs.analchem.3c04211. Epub 2024 Jan 2. Anal Chem. 2024. PMID: 38165811
Chaotropic Effects in Sub/Supercritical Fluid Chromatography via Ammonium Hydroxide in Water-Rich Modifiers: Enabling Separation of Peptides and Highly Polar Pharmaceuticals at the Preparative Scale.
Liu J, Makarov AA, Bennett R, Haidar Ahmad IA, DaSilva J, Reibarkh M, Mangion I, Mann BF, Regalado EL. Liu J, et al. Among authors: regalado el. Anal Chem. 2019 Nov 5;91(21):13907-13915. doi: 10.1021/acs.analchem.9b03408. Epub 2019 Oct 8. Anal Chem. 2019. PMID: 31549812
Automated ion exchange chromatography screening combined with in silico multifactorial simulation for efficient method development and purification of biopharmaceutical targets.
Losacco GL, Hicks MB, DaSilva JO, Wang H, Potapenko M, Tsay FR, Ahmad IAH, Mangion I, Guillarme D, Regalado EL. Losacco GL, et al. Among authors: regalado el. Anal Bioanal Chem. 2022 May;414(12):3581-3591. doi: 10.1007/s00216-022-03982-z. Epub 2022 Apr 20. Anal Bioanal Chem. 2022. PMID: 35441858
Synthesis of a Complex and Highly Potent PCSK9 Inhibitor.
Kuethe JT, Lee J, Thaisrivongs D, Yasuda N, Pollack SR, Leone J, DaSilva J, Biba M, Tsay FR, Regalado EL, Qi J, Li H, Poggetto GD, Cohen R. Kuethe JT, et al. Among authors: regalado el. Org Lett. 2023 Jul 14;25(27):5001-5005. doi: 10.1021/acs.orglett.3c01635. Epub 2023 Jun 29. Org Lett. 2023. PMID: 37382389
89 results