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One-carbon metabolite supplementation to heifers for the first 14 d of the estrous cycle alters the plasma and hepatic one-carbon metabolite pool and methionine-folate cycle enzyme transcript abundance in a dose-dependent manner.
Crouse MS, Freetly HC, Lindholm-Perry AK, Neville BW, Oliver WT, Lee RT, Syring JG, King LE, Reynolds LP, Dahlen CR, Caton JS, Ward AK, Cushman RA. Crouse MS, et al. Among authors: syring jg. J Anim Sci. 2023 Jan 3;101:skac419. doi: 10.1093/jas/skac419. J Anim Sci. 2023. PMID: 36566452 Free PMC article.
Concentrations of vitamin B12 and folate in maternal serum and fetal fluids, metabolite interrelationships, and hepatic transcript abundance of key folate and methionine cycle genes: the impacts of maternal nutrition during the first 50 d of gestation.
Syring JG, Crouse MS, Neville TL, Ward AK, Dahlen CR, Reynolds LP, Borowicz PP, McLean KJ, Neville BW, Caton JS. Syring JG, et al. J Anim Sci. 2023 Jan 3;101:skad139. doi: 10.1093/jas/skad139. J Anim Sci. 2023. PMID: 37129588 Free PMC article.
Disrupted one-carbon metabolism in heifers negatively affects their health and physiology.
Crouse MS, Trotta RJ, Freetly HC, Lindholm-Perry AK, Neville BW, Oliver WT, Hammer CJ, Syring JG, King LE, Neville TL, Reynolds LP, Dahlen CR, Caton JS, Ward AK, Cushman RA. Crouse MS, et al. Among authors: syring jg. J Anim Sci. 2024 May 21:skae144. doi: 10.1093/jas/skae144. Online ahead of print. J Anim Sci. 2024. PMID: 38770669