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Detection of Active SARS-CoV-2 3CL Protease in Infected Cells Using Activity-Based Probes with a 2,6-Dichlorobenzoyloxymethyl Ketone Reactive Warhead.
ACS Chem Biol. 2024 May 17;19(5):1028-1034. doi: 10.1021/acschembio.4c00024. Epub 2024 Apr 26.
ACS Chem Biol. 2024.
PMID: 38668705
Combinatorial assembly, traceless generation and in situ evaluation of inhibitors for therapeutically relevant serine proteases.
Vu LP, Zyulina M, Hingst A, Schnakenburg G, Gütschow M.
Vu LP, et al. Among authors: hingst a.
Bioorg Chem. 2022 Apr;121:105676. doi: 10.1016/j.bioorg.2022.105676. Epub 2022 Feb 11.
Bioorg Chem. 2022.
PMID: 35202850
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Macrocyclic Azapeptide Nitriles: Structure-Based Discovery of Potent SARS-CoV-2 Main Protease Inhibitors as Antiviral Drugs.
Breidenbach J, Voget R, Si Y, Hingst A, Claff T, Sylvester K, Wolf V, Krasniqi V, Useini A, Sträter N, Ogura Y, Kawaguchi A, Müller CE, Gütschow M.
Breidenbach J, et al. Among authors: hingst a.
J Med Chem. 2024 May 16. doi: 10.1021/acs.jmedchem.4c00053. Online ahead of print.
J Med Chem. 2024.
PMID: 38753594
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Development of an active-site titrant for SARS-CoV-2 main protease as an indispensable tool for evaluating enzyme kinetics.
Voget R, Breidenbach J, Claff T, Hingst A, Sylvester K, Steinebach C, Vu LP, Weiße RH, Bartz U, Sträter N, Müller CE, Gütschow M.
Voget R, et al. Among authors: hingst a.
Acta Pharm Sin B. 2024 May;14(5):2349-2357. doi: 10.1016/j.apsb.2024.03.001. Epub 2024 Mar 6.
Acta Pharm Sin B. 2024.
PMID: 38799620
Free PMC article.
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Identification of pentatricopeptide repeat proteins in Trypanosoma brucei.
Mingler MK, Hingst AM, Clement SL, Yu LE, Reifur L, Koslowsky DJ.
Mingler MK, et al. Among authors: hingst am.
Mol Biochem Parasitol. 2006 Nov;150(1):37-45. doi: 10.1016/j.molbiopara.2006.06.006. Epub 2006 Jun 28.
Mol Biochem Parasitol. 2006.
PMID: 16837079
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Matching therapists' predicates: an in vivo test of effectiveness.
Dowd ET, Hingst AG.
Dowd ET, et al. Among authors: hingst ag.
Percept Mot Skills. 1983 Aug;57(1):207-10. doi: 10.2466/pms.1983.57.1.207.
Percept Mot Skills. 1983.
PMID: 6622159
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