Tainer JA - Search Results

1

Chemical screening by time-resolved X-ray scattering to discover allosteric probes.

Brosey CA, Link TM, Shen R, Moiani D, Burnett K, Hura GL, Jones DE, Tainer JA. Brosey CA, et al. Among authors: tainer ja. Nat Chem Biol. 2024 Apr 26. doi: 10.1038/s41589-024-01609-1. Online ahead of print. Nat Chem Biol. 2024. PMID: 38671223

2

A flexible interface between DNA ligase and PCNA supports conformational switching and efficient ligation of DNA.

Pascal JM, Tsodikov OV, Hura GL, Song W, Cotner EA, Classen S, Tomkinson AE, Tainer JA, Ellenberger T. Pascal JM, et al. Among authors: tainer ja. Mol Cell. 2006 Oct 20;24(2):279-91. doi: 10.1016/j.molcel.2006.08.015. Mol Cell. 2006. PMID: 17052461 Free article.

3

Structural analysis of flexible proteins in solution by small angle X-ray scattering combined with crystallography.

Tsutakawa SE, Hura GL, Frankel KA, Cooper PK, Tainer JA. Tsutakawa SE, et al. Among authors: tainer ja. J Struct Biol. 2007 May;158(2):214-23. doi: 10.1016/j.jsb.2006.09.008. Epub 2006 Oct 27. J Struct Biol. 2007. PMID: 17182256

4

X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution.

Putnam CD, Hammel M, Hura GL, Tainer JA. Putnam CD, et al. Among authors: tainer ja. Q Rev Biophys. 2007 Aug;40(3):191-285. doi: 10.1017/S0033583507004635. Q Rev Biophys. 2007. PMID: 18078545 Review.

5

Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1.

Chrencik JE, Brooun A, Zhang H, Mathews II, Hura GL, Foster SA, Perry JJ, Streiff M, Ramage P, Widmer H, Bokoch GM, Tainer JA, Weckbecker G, Kuhn P. Chrencik JE, et al. Among authors: tainer ja. J Mol Biol. 2008 Jul 25;380(5):828-43. doi: 10.1016/j.jmb.2008.05.024. Epub 2008 May 17. J Mol Biol. 2008. PMID: 18589439 Free PMC article.

6

Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair.

Williams RS, Moncalian G, Williams JS, Yamada Y, Limbo O, Shin DS, Groocock LM, Cahill D, Hitomi C, Guenther G, Moiani D, Carney JP, Russell P, Tainer JA. Williams RS, et al. Among authors: tainer ja. Cell. 2008 Oct 3;135(1):97-109. doi: 10.1016/j.cell.2008.08.017. Cell. 2008. PMID: 18854158 Free PMC article.

7

Superoxide dismutase from the eukaryotic thermophile Alvinella pompejana: structures, stability, mechanism, and insights into amyotrophic lateral sclerosis.

Shin DS, Didonato M, Barondeau DP, Hura GL, Hitomi C, Berglund JA, Getzoff ED, Cary SC, Tainer JA. Shin DS, et al. Among authors: tainer ja. J Mol Biol. 2009 Feb 6;385(5):1534-55. doi: 10.1016/j.jmb.2008.11.031. Epub 2008 Nov 25. J Mol Biol. 2009. PMID: 19063897 Free PMC article.

8

p38alpha MAP kinase C-terminal domain binding pocket characterized by crystallographic and computational analyses.

Perry JJ, Harris RM, Moiani D, Olson AJ, Tainer JA. Perry JJ, et al. Among authors: tainer ja. J Mol Biol. 2009 Aug 7;391(1):1-11. doi: 10.1016/j.jmb.2009.06.005. Epub 2009 Jun 6. J Mol Biol. 2009. PMID: 19501598 Free PMC article.

9

Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS).

Hura GL, Menon AL, Hammel M, Rambo RP, Poole FL 2nd, Tsutakawa SE, Jenney FE Jr, Classen S, Frankel KA, Hopkins RC, Yang SJ, Scott JW, Dillard BD, Adams MW, Tainer JA. Hura GL, et al. Among authors: tainer ja. Nat Methods. 2009 Aug;6(8):606-12. doi: 10.1038/nmeth.1353. Epub 2009 Jul 20. Nat Methods. 2009. PMID: 19620974 Free PMC article.

10

Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex.

Hammel M, Yu Y, Mahaney BL, Cai B, Ye R, Phipps BM, Rambo RP, Hura GL, Pelikan M, So S, Abolfath RM, Chen DJ, Lees-Miller SP, Tainer JA. Hammel M, et al. Among authors: tainer ja. J Biol Chem. 2010 Jan 8;285(2):1414-23. doi: 10.1074/jbc.M109.065615. Epub 2009 Nov 5. J Biol Chem. 2010. PMID: 19893054 Free PMC article.

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