Cosconati S - Search Results

1

Development of Novel Peptidyl Nitriles Targeting Rhodesain and Falcipain-2 for the Treatment of Sleeping Sickness and Malaria.

Di Chio C, Starvaggi J, Totaro N, Previti S, Natale B, Cosconati S, Bogacz M, Schirmeister T, Legac J, Rosenthal PJ, Zappalà M, Ettari R. Di Chio C, et al. Among authors: cosconati s. Int J Mol Sci. 2024 Apr 17;25(8):4410. doi: 10.3390/ijms25084410. Int J Mol Sci. 2024. PMID: 38673995 Free PMC article.

2

Elucidation of the enantioselective recognition mechanism of a penicillin G acylase-based chiral stationary phase towards a series of 2-aryloxy-2-arylacetic acids.

Massolini G, Fracchiolla G, Calleri E, Carbonara G, Temporini C, Lavecchia A, Cosconati S, Novellino E, Loiodice F. Massolini G, et al. Among authors: cosconati s. Chirality. 2006 Aug;18(8):633-43. doi: 10.1002/chir.20300. Chirality. 2006. PMID: 16715517

3

SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.

Rizzo A, Iachettini S, Salvati E, Zizza P, Maresca C, D'Angelo C, Benarroch-Popivker D, Capolupo A, Del Gaudio F, Cosconati S, Di Maro S, Merlino F, Novellino E, Amoreo CA, Mottolese M, Sperduti I, Gilson E, Biroccio A. Rizzo A, et al. Among authors: cosconati s. Nucleic Acids Res. 2017 Feb 28;45(4):1820-1834. doi: 10.1093/nar/gkw1202. Nucleic Acids Res. 2017. PMID: 27923994 Free PMC article.

4

Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides.

Barresi E, Bruno A, Taliani S, Cosconati S, Da Pozzo E, Salerno S, Simorini F, Daniele S, Giacomelli C, Marini AM, La Motta C, Marinelli L, Cosimelli B, Novellino E, Greco G, Da Settimo F, Martini C. Barresi E, et al. Among authors: cosconati s. J Med Chem. 2015 Aug 13;58(15):6081-92. doi: 10.1021/acs.jmedchem.5b00689. Epub 2015 Jul 28. J Med Chem. 2015. PMID: 26177193

5

Ligand based approach to L-type calcium channel by imidazo[2,1-b]thiazole-1,4-dihydropyridines: from heart activity to brain affinity.

Locatelli A, Cosconati S, Micucci M, Leoni A, Marinelli L, Bedini A, Ioan P, Spampinato SM, Novellino E, Chiarini A, Budriesi R. Locatelli A, et al. Among authors: cosconati s. J Med Chem. 2013 May 23;56(10):3866-77. doi: 10.1021/jm301839q. Epub 2013 May 9. J Med Chem. 2013. PMID: 23586669

6

Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells.

Valente S, Liu Y, Schnekenburger M, Zwergel C, Cosconati S, Gros C, Tardugno M, Labella D, Florean C, Minden S, Hashimoto H, Chang Y, Zhang X, Kirsch G, Novellino E, Arimondo PB, Miele E, Ferretti E, Gulino A, Diederich M, Cheng X, Mai A. Valente S, et al. Among authors: cosconati s. J Med Chem. 2014 Feb 13;57(3):701-13. doi: 10.1021/jm4012627. Epub 2014 Jan 15. J Med Chem. 2014. PMID: 24387159 Free PMC article.

7

4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching.

Leoni A, Frosini M, Locatelli A, Micucci M, Carotenuto C, Durante M, Cosconati S, Budriesi R. Leoni A, et al. Among authors: cosconati s. Eur J Med Chem. 2019 May 1;169:89-102. doi: 10.1016/j.ejmech.2019.02.075. Epub 2019 Mar 4. Eur J Med Chem. 2019. PMID: 30861492

8

Synthesis and biological evaluation of novel peptidomimetics as rhodesain inhibitors.

Ettari R, Previti S, Cosconati S, Kesselring J, Schirmeister T, Grasso S, Zappalà M. Ettari R, et al. Among authors: cosconati s. J Enzyme Inhib Med Chem. 2016 Dec;31(6):1184-91. doi: 10.3109/14756366.2015.1108972. Epub 2015 Nov 16. J Enzyme Inhib Med Chem. 2016. PMID: 26572904

9

Development of novel 1,4-benzodiazepine-based Michael acceptors as antitrypanosomal agents.

Ettari R, Previti S, Cosconati S, Maiorana S, Schirmeister T, Grasso S, Zappalà M. Ettari R, et al. Among authors: cosconati s. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3453-6. doi: 10.1016/j.bmcl.2016.06.047. Epub 2016 Jun 21. Bioorg Med Chem Lett. 2016. PMID: 27372809

10

Development of Novel Peptide-Based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs).

Previti S, Ettari R, Cosconati S, Amendola G, Chouchene K, Wagner A, Hellmich UA, Ulrich K, Krauth-Siegel RL, Wich PR, Schmid I, Schirmeister T, Gut J, Rosenthal PJ, Grasso S, Zappalà M. Previti S, et al. Among authors: cosconati s. J Med Chem. 2017 Aug 24;60(16):6911-6923. doi: 10.1021/acs.jmedchem.7b00405. Epub 2017 Aug 11. J Med Chem. 2017. PMID: 28763614

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