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Comparison of anti-SARS-CoV-2 activity and intracellular metabolism of remdesivir and its parent nucleoside.
Tao S, Zandi K, Bassit L, Ong YT, Verma K, Liu P, Downs-Bowen JA, McBrayer T, LeCher JC, Kohler JJ, Tedbury PR, Kim B, Amblard F, Sarafianos SG, Schinazi RF. Tao S, et al. Among authors: kohler jj. Curr Res Pharmacol Drug Discov. 2021;2:100045. doi: 10.1016/j.crphar.2021.100045. Epub 2021 Aug 12. Curr Res Pharmacol Drug Discov. 2021. PMID: 34870151 Free PMC article.
Nucleoside Analogs with Selective Antiviral Activity against Dengue Fever and Japanese Encephalitis Viruses.
Zandi K, Bassit L, Amblard F, Cox BD, Hassandarvish P, Moghaddam E, Yueh A, Libanio Rodrigues GO, Passos I, Costa VV, AbuBakar S, Zhou L, Kohler J, Teixeira MM, Schinazi RF. Zandi K, et al. Antimicrob Agents Chemother. 2019 Jun 24;63(7):e00397-19. doi: 10.1128/AAC.00397-19. Print 2019 Jul. Antimicrob Agents Chemother. 2019. PMID: 31061163 Free PMC article.
Discovery of a 2'-Fluoro,2'-Bromouridine Phosphoramidate Prodrug Exhibiting Anti-Yellow Fever Virus Activity in Culture and in Mice.
LeCher JC, Zandi K, Costa VV, Amblard F, Tao S, Patel D, Lee S, da Silva Santos FR, Goncalves MR, Queroz-Junior CM, Marim FM, Musall K, Goh SL, McBrayer T, Downs-Bowen J, De R, Azadi N, Kohler J, Teixeira MM, Schinazi RF. LeCher JC, et al. Microorganisms. 2022 Oct 22;10(11):2098. doi: 10.3390/microorganisms10112098. Microorganisms. 2022. PMID: 36363688 Free PMC article.
Approaches to hepatitis C treatment and cure using NS5A inhibitors.
Kohler JJ, Nettles JH, Amblard F, Hurwitz SJ, Bassit L, Stanton RA, Ehteshami M, Schinazi RF. Kohler JJ, et al. Infect Drug Resist. 2014 Mar 5;7:41-56. doi: 10.2147/IDR.S36247. eCollection 2014. Infect Drug Resist. 2014. PMID: 24623983 Free PMC article. Review.
Evaluation of single and combination therapies with tenofovir disoproxil fumarate and emtricitabine in vitro and in a robust mouse model supporting high levels of hepatitis B virus replication.
Schinazi RF, Bassit L, Clayton MM, Sun B, Kohler JJ, Obikhod A, Arzumanyan A, Feitelson MA. Schinazi RF, et al. Among authors: kohler jj. Antimicrob Agents Chemother. 2012 Dec;56(12):6186-91. doi: 10.1128/AAC.01483-12. Epub 2012 Sep 17. Antimicrob Agents Chemother. 2012. PMID: 22985879 Free PMC article.
Pharmacokinetics of Ruxolitinib in HIV Suppressed Individuals on Antiretroviral Agent Therapy from the ACTG A5336 Study.
Hurwitz SJ, Tao S, Gavegnano C, Jiang Y, Tressler RL, Tsibris A, Del Rio C, Overton ET, Lederman MM, Kantor A, Moser C, Kohler JJ, Lennox J, Marconi VC, Flexner CW, Schinazi RF. Hurwitz SJ, et al. Among authors: kohler jj. J Clin Pharmacol. 2021 Dec;61(12):1555-1566. doi: 10.1002/jcph.1930. Epub 2021 Jul 23. J Clin Pharmacol. 2021. PMID: 34169526 Free PMC article. Clinical Trial.
138 results