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A novel mechanism of idiopathic orthostatic hypotension and hypocatecholaminemia due to autoimmunity against aromatic l-Amino acid decarboxylase.
Uenishi E, Seino Y, Nakashima A, Kato K, Kato M, Nagasaki H, Ishikawa K, Izumoto T, Yamamoto M, Takahashi Y, Sugimura Y, Oiso Y, Tsunekawa S. Uenishi E, et al. Among authors: ishikawa k. Biochem Biophys Res Commun. 2024 Jun 25;714:149940. doi: 10.1016/j.bbrc.2024.149940. Epub 2024 Apr 16. Biochem Biophys Res Commun. 2024. PMID: 38677008
Effect of hyperglycemia on hepatocellular carcinoma development in diabetes.
Niwa Y, Ishikawa K, Ishigami M, Honda T, Achiwa K, Izumoto T, Maekawa R, Hosokawa K, Iida A, Seino Y, Hamada Y, Goto H, Oiso Y, Arima H, Tsunekawa S. Niwa Y, et al. Among authors: ishikawa k. Biochem Biophys Res Commun. 2015 Jul 31;463(3):344-50. doi: 10.1016/j.bbrc.2015.05.066. Epub 2015 May 28. Biochem Biophys Res Commun. 2015. PMID: 26022129 Free article.
Long-term pancreatic beta cell exposure to high levels of glucose but not palmitate induces DNA methylation within the insulin gene promoter and represses transcriptional activity.
Ishikawa K, Tsunekawa S, Ikeniwa M, Izumoto T, Iida A, Ogata H, Uenishi E, Seino Y, Ozaki N, Sugimura Y, Hamada Y, Kuroda A, Shinjo K, Kondo Y, Oiso Y. Ishikawa K, et al. PLoS One. 2015 Feb 6;10(2):e0115350. doi: 10.1371/journal.pone.0115350. eCollection 2015. PLoS One. 2015. PMID: 25658116 Free PMC article.
Secreted factors from dental pulp stem cells improve glucose intolerance in streptozotocin-induced diabetic mice by increasing pancreatic β-cell function.
Izumoto-Akita T, Tsunekawa S, Yamamoto A, Uenishi E, Ishikawa K, Ogata H, Iida A, Ikeniwa M, Hosokawa K, Niwa Y, Maekawa R, Yamauchi Y, Seino Y, Hamada Y, Hibi H, Arima H, Ueda M, Oiso Y. Izumoto-Akita T, et al. Among authors: ishikawa k. BMJ Open Diabetes Res Care. 2015 Oct 19;3(1):e000128. doi: 10.1136/bmjdrc-2015-000128. eCollection 2015. BMJ Open Diabetes Res Care. 2015. PMID: 26504525 Free PMC article.
Ingestion of a moderate high-sucrose diet results in glucose intolerance with reduced liver glucokinase activity and impaired glucagon-like peptide-1 secretion.
Sakamoto E, Seino Y, Fukami A, Mizutani N, Tsunekawa S, Ishikawa K, Ogata H, Uenishi E, Kamiya H, Hamada Y, Sato H, Harada N, Toyoda Y, Miwa I, Nakamura J, Inagaki N, Oiso Y, Ozaki N. Sakamoto E, et al. Among authors: ishikawa k. J Diabetes Investig. 2012 Oct 18;3(5):432-40. doi: 10.1111/j.2040-1124.2012.00208.x. J Diabetes Investig. 2012. PMID: 24843603 Free PMC article.
KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state.
Ogata H, Seino Y, Harada N, Iida A, Suzuki K, Izumoto T, Ishikawa K, Uenishi E, Ozaki N, Hayashi Y, Miki T, Inagaki N, Tsunekawa S, Hamada Y, Seino S, Oiso Y. Ogata H, et al. Among authors: ishikawa k. J Endocrinol. 2014 Aug;222(2):191-200. doi: 10.1530/JOE-14-0161. Epub 2014 Jun 2. J Endocrinol. 2014. PMID: 24891433
Endogenous GIP ameliorates impairment of insulin secretion in proglucagon-deficient mice under moderate beta cell damage induced by streptozotocin.
Iida A, Seino Y, Fukami A, Maekawa R, Yabe D, Shimizu S, Kinoshita K, Takagi Y, Izumoto T, Ogata H, Ishikawa K, Ozaki N, Tsunekawa S, Hamada Y, Oiso Y, Arima H, Hayashi Y. Iida A, et al. Among authors: ishikawa k. Diabetologia. 2016 Jul;59(7):1533-1541. doi: 10.1007/s00125-016-3935-2. Epub 2016 Apr 6. Diabetologia. 2016. PMID: 27053237 Free PMC article.
4,384 results