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A novel mechanism of idiopathic orthostatic hypotension and hypocatecholaminemia due to autoimmunity against aromatic l-Amino acid decarboxylase.
Uenishi E, Seino Y, Nakashima A, Kato K, Kato M, Nagasaki H, Ishikawa K, Izumoto T, Yamamoto M, Takahashi Y, Sugimura Y, Oiso Y, Tsunekawa S. Uenishi E, et al. Among authors: sugimura y. Biochem Biophys Res Commun. 2024 Jun 25;714:149940. doi: 10.1016/j.bbrc.2024.149940. Epub 2024 Apr 16. Biochem Biophys Res Commun. 2024. PMID: 38677008
Long-term pancreatic beta cell exposure to high levels of glucose but not palmitate induces DNA methylation within the insulin gene promoter and represses transcriptional activity.
Ishikawa K, Tsunekawa S, Ikeniwa M, Izumoto T, Iida A, Ogata H, Uenishi E, Seino Y, Ozaki N, Sugimura Y, Hamada Y, Kuroda A, Shinjo K, Kondo Y, Oiso Y. Ishikawa K, et al. Among authors: sugimura y. PLoS One. 2015 Feb 6;10(2):e0115350. doi: 10.1371/journal.pone.0115350. eCollection 2015. PLoS One. 2015. PMID: 25658116 Free PMC article.
High Protein Diet Feeding Aggravates Hyperaminoacidemia in Mice Deficient in Proglucagon-Derived Peptides.
Ueno S, Seino Y, Hidaka S, Maekawa R, Takano Y, Yamamoto M, Hori M, Yokota K, Masuda A, Himeno T, Tsunekawa S, Kamiya H, Nakamura J, Kuwata H, Fujisawa H, Shibata M, Takayanagi T, Sugimura Y, Yabe D, Hayashi Y, Suzuki A. Ueno S, et al. Among authors: sugimura y. Nutrients. 2022 Feb 25;14(5):975. doi: 10.3390/nu14050975. Nutrients. 2022. PMID: 35267952 Free PMC article.
577 results