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Correction: Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis.
Oncogene. 2024 Apr 27. doi: 10.1038/s41388-024-03046-9. Online ahead of print.
Oncogene. 2024.
PMID: 38678124
No abstract available.
TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment.
Sirkisoon SR, Carpenter RL, Rimkus T, Doheny D, Zhu D, Aguayo NR, Xing F, Chan M, Ruiz J, Metheny-Barlow LJ, Strowd R, Lin J, Regua AT, Arrigo A, Anguelov M, Pasche B, Debinski W, Watabe K, Lo HW.
Sirkisoon SR, et al. Among authors: aguayo nr.
Oncogene. 2020 Jan;39(1):64-78. doi: 10.1038/s41388-019-0959-3. Epub 2019 Aug 28.
Oncogene. 2020.
PMID: 31462709
Free PMC article.
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Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis.
Doheny D, Sirkisoon S, Carpenter RL, Aguayo NR, Regua AT, Anguelov M, Manore SG, Arrigo A, Jalboush SA, Wong GL, Yu Y, Wagner CJ, Chan M, Ruiz J, Thomas A, Strowd R, Lin J, Lo HW.
Doheny D, et al. Among authors: aguayo nr.
Oncogene. 2020 Oct;39(42):6589-6605. doi: 10.1038/s41388-020-01454-1. Epub 2020 Sep 14.
Oncogene. 2020.
PMID: 32929154
Free PMC article.
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Correction: TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment.
Sirkisoon SR, Carpenter RL, Rimkus T, Doheny D, Zhu D, Aguayo NR, Xing F, Chan M, Ruiz J, Metheny-Barlow LJ, Strowd R, Lin J, Regua AT, Arrigo A, Anguelov M, Pasche B, Debinski W, Watabe K, Lo HW.
Sirkisoon SR, et al. Among authors: aguayo nr.
Oncogene. 2021 Mar;40(12):2338. doi: 10.1038/s41388-020-01620-5.
Oncogene. 2021.
PMID: 33654200
No abstract available.
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TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast Cancers.
Regua AT, Aguayo NR, Jalboush SA, Doheny DL, Manore SG, Zhu D, Wong GL, Arrigo A, Wagner CJ, Yu Y, Thomas A, Chan MD, Ruiz J, Jin G, Strowd R, Sun P, Lin J, Lo HW.
Regua AT, et al. Among authors: aguayo nr.
Cancers (Basel). 2021 May 12;13(10):2340. doi: 10.3390/cancers13102340.
Cancers (Basel). 2021.
PMID: 34066153
Free PMC article.
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Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→CNTF axis to promote progression of brain metastases.
Sirkisoon SR, Wong GL, Aguayo NR, Doheny DL, Zhu D, Regua AT, Arrigo A, Manore SG, Wagner C, Thomas A, Singh R, Xing F, Jin G, Watabe K, Lo HW.
Sirkisoon SR, et al. Among authors: aguayo nr.
Cancer Lett. 2022 Aug 1;540:215726. doi: 10.1016/j.canlet.2022.215726. Epub 2022 May 16.
Cancer Lett. 2022.
PMID: 35589002
Free PMC article.
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An FDA-Approved Antifungal, Ketoconazole, and Its Novel Derivative Suppress tGLI1-Mediated Breast Cancer Brain Metastasis by Inhibiting the DNA-Binding Activity of Brain Metastasis-Promoting Transcription Factor tGLI1.
Doheny D, Manore S, Sirkisoon SR, Zhu D, Aguayo NR, Harrison A, Najjar M, Anguelov M, Cox AO, Furdui CM, Watabe K, Hollis T, Thomas A, Strowd R, Lo HW.
Doheny D, et al. Among authors: aguayo nr.
Cancers (Basel). 2022 Aug 31;14(17):4256. doi: 10.3390/cancers14174256.
Cancers (Basel). 2022.
PMID: 36077791
Free PMC article.
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