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The single intravenous administration of methylene blue after traumatic brain injury diminishes neurological deficit, blood-brain barrier disruption and decrease in the expression of S100 protein in rats.
Genrikhs EE, Stelmashook EV, Voronkov DN, Novikova SV, Alexandrova OP, Fedorov AV, Isaev NK. Genrikhs EE, et al. Among authors: isaev nk. Brain Res. 2020 Aug 1;1740:146854. doi: 10.1016/j.brainres.2020.146854. Epub 2020 Apr 25. Brain Res. 2020. PMID: 32339501
Mitochondria-targeted antioxidant SkQT1 decreases trauma-induced neurological deficit in rat and prevents amyloid-β-induced impairment of long-term potentiation in rat hippocampal slices.
Genrikhs EE, Stelmashook EV, Popova OV, Kapay NA, Korshunova GA, Sumbatyan NV, Skrebitsky VG, Skulachev VP, Isaev NK. Genrikhs EE, et al. Among authors: isaev nk. J Drug Target. 2015 May;23(4):347-52. doi: 10.3109/1061186X.2014.997736. Epub 2015 Jan 14. J Drug Target. 2015. PMID: 25585580
Streptozotocin toxicity in vitro depends on maturity of neurons.
Isaev NK, Genrikhs EE, Voronkov DN, Kapkaeva MR, Stelmashook EV. Isaev NK, et al. Toxicol Appl Pharmacol. 2018 Jun 1;348:99-104. doi: 10.1016/j.taap.2018.04.024. Epub 2018 Apr 20. Toxicol Appl Pharmacol. 2018. PMID: 29684395
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