Shen R - Search Results

1

Topical hidden genome: discovering latent cancer mutational topics using a Bayesian multilevel context-learning approach.

Chakraborty S, Guan Z, Begg CB, Shen R. Chakraborty S, et al. Among authors: shen r. Biometrics. 2024 Mar 27;80(2):ujae030. doi: 10.1093/biomtc/ujae030. Biometrics. 2024. PMID: 38682463

2

Using the "Hidden" genome to improve classification of cancer types.

Chakraborty S, Begg CB, Shen R. Chakraborty S, et al. Among authors: shen r. Biometrics. 2021 Dec;77(4):1445-1455. doi: 10.1111/biom.13367. Epub 2020 Sep 21. Biometrics. 2021. PMID: 32914442 Free PMC article.

3

Mining mutation contexts across the cancer genome to map tumor site of origin.

Chakraborty S, Martin A, Guan Z, Begg CB, Shen R. Chakraborty S, et al. Among authors: shen r. Nat Commun. 2021 May 24;12(1):3051. doi: 10.1038/s41467-021-23094-z. Nat Commun. 2021. PMID: 34031376 Free PMC article.

4

Predicting Cancer Risk from Germline Whole-exome Sequencing Data Using a Novel Context-based Variant Aggregation Approach.

Guan Z, Begg CB, Shen R. Guan Z, et al. Among authors: shen r. Cancer Res Commun. 2023 Mar 22;3(3):483-488. doi: 10.1158/2767-9764.CRC-22-0355. eCollection 2023 Mar. Cancer Res Commun. 2023. PMID: 36969913 Free PMC article.

5

An efficient basket trial design.

Cunanan KM, Iasonos A, Shen R, Begg CB, Gönen M. Cunanan KM, et al. Among authors: shen r. Stat Med. 2017 May 10;36(10):1568-1579. doi: 10.1002/sim.7227. Epub 2017 Jan 18. Stat Med. 2017. PMID: 28098411 Free PMC article.

6

Using somatic variant richness to mine signals from rare variants in the cancer genome.

Chakraborty S, Arora A, Begg CB, Shen R. Chakraborty S, et al. Among authors: shen r. Nat Commun. 2019 Dec 3;10(1):5506. doi: 10.1038/s41467-019-13402-z. Nat Commun. 2019. PMID: 31796730 Free PMC article.

7

Human genes differ by their UV sensitivity estimated through analysis of UV-induced silent mutations in melanoma.

Gorlov IP, Amos CI, Tsavachidis S, Begg C, Hernando E, Cheng C, Shen R, Orlow I, Luo L, Ernstoff MS, Parker J, Thomas NE, Gorlova OY, Berwick M. Gorlov IP, et al. Among authors: shen r. Hum Mutat. 2020 Oct;41(10):1751-1760. doi: 10.1002/humu.24078. Epub 2020 Jul 15. Hum Mutat. 2020. PMID: 32643855 Free PMC article.

8

Exome-Wide Pan-Cancer Analysis of Germline Variants in 8,719 Individuals Finds Little Evidence of Rare Variant Associations.

Guan Z, Shen R, Begg CB. Guan Z, et al. Among authors: shen r. Hum Hered. 2021;86(1-4):34-44. doi: 10.1159/000519355. Epub 2021 Oct 29. Hum Hered. 2021. PMID: 34718237 Free PMC article.

9

Landscape of mutations in early stage primary cutaneous melanoma: An InterMEL study.

Luo L, Shen R, Arora A, Orlow I, Busam KJ, Lezcano C, Lee TK, Hernando E, Gorlov I, Amos C, Ernstoff MS, Seshan VE, Cust AE, Wilmott J, Scolyer RA, Mann G, Nagore E, Funchain P, Ko J, Ngo P, Edmiston SN, Conway K, Googe PB, Ollila D, Lee JE, Fang S, Rees JR, Thompson CL, Gerstenblith M, Bosenberg M, Gould Rothberg B, Osman I, Saenger Y, Reynolds AZ, Schwartz M, Boyce T, Holmen S, Brunsgaard E, Bogner P, Kuan PF, Wiggins C, Thomas NE, Begg CB, Berwick M; InterMEL. Luo L, et al. Among authors: shen r. Pigment Cell Melanoma Res. 2022 Nov;35(6):605-612. doi: 10.1111/pcmr.13058. Epub 2022 Aug 12. Pigment Cell Melanoma Res. 2022. PMID: 35876628 Free PMC article.

10

Pathway Alterations in Stage II/III Primary Melanoma.

Kostrzewa CE, Luo L, Arora A, Seshan VE, Ernstoff MS, Edmiston SN, Conway K, Gorlov I, Busam K, Orlow I, Hernando-Monge E, Thomas NE, Berwick M, Begg CB, Shen R; for InterMEL. Kostrzewa CE, et al. Among authors: shen r. JCO Precis Oncol. 2023 Mar;7:e2200439. doi: 10.1200/PO.22.00439. JCO Precis Oncol. 2023. PMID: 36926987 Free PMC article.

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