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430 results

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Page 1
In vivo rescue of genetic dilated cardiomyopathy by systemic delivery of nexilin.
Shao Y, Liu C, Liao HK, Zhang R, Yuan B, Yang H, Li R, Zhu S, Fang X, Rodriguez Esteban C, Chen J, Izpisua Belmonte JC. Shao Y, et al. Among authors: izpisua belmonte jc. Genome Biol. 2024 May 23;25(1):135. doi: 10.1186/s13059-024-03283-x. Genome Biol. 2024. PMID: 38783323 Free PMC article.
Modulation of the microhomology-mediated end joining pathway suppresses large deletions and enhances homology-directed repair following CRISPR-Cas9-induced DNA breaks.
Yuan B, Bi C, Tian Y, Wang J, Jin Y, Alsayegh K, Tehseen M, Yi G, Zhou X, Shao Y, Romero FV, Fischle W, Izpisua Belmonte JC, Hamdan S, Huang Y, Li M. Yuan B, et al. Among authors: izpisua belmonte jc. BMC Biol. 2024 Apr 29;22(1):101. doi: 10.1186/s12915-024-01896-z. BMC Biol. 2024. PMID: 38685010 Free PMC article.
Functional sensory circuits built from neurons of two species.
Throesch BT, Bin Imtiaz MK, Muñoz-Castañeda R, Sakurai M, Hartzell AL, James KN, Rodriguez AR, Martin G, Lippi G, Kupriyanov S, Wu Z, Osten P, Izpisua Belmonte JC, Wu J, Baldwin KK. Throesch BT, et al. Among authors: izpisua belmonte jc. Cell. 2024 Apr 25;187(9):2143-2157.e15. doi: 10.1016/j.cell.2024.03.042. Cell. 2024. PMID: 38670072
Intervention with metabolites emulating endogenous cell transitions accelerates muscle regeneration in young and aged mice.
Hernandez-Benitez R, Wang C, Shi L, Ouchi Y, Zhong C, Hishida T, Liao HK, Magill EA, Memczak S, Soligalla RD, Fresia C, Hatanaka F, Lamas V, Guillen I, Sahu S, Yamamoto M, Shao Y, Aguirre-Vazquez A, Nuñez Delicado E, Guillen P, Rodriguez Esteban C, Qu J, Reddy P, Horvath S, Liu GH, Magistretti P, Izpisua Belmonte JC. Hernandez-Benitez R, et al. Among authors: izpisua belmonte jc. Cell Rep Med. 2024 Mar 19;5(3):101449. doi: 10.1016/j.xcrm.2024.101449. Cell Rep Med. 2024. PMID: 38508141 Free PMC article.
Aging induces region-specific dysregulation of hormone synthesis in the primate adrenal gland.
Wang Q, Wang X, Liu B, Ma S, Zhang F, Sun S, Jing Y, Fan Y, Ding Y, Xiong M, Li J, Zhai Q, Zheng Y, Liu C, Xu G, Yang J, Wang S, Ye J, Izpisua Belmonte JC, Qu J, Liu GH, Zhang W. Wang Q, et al. Among authors: izpisua belmonte jc. Nat Aging. 2024 Mar;4(3):396-413. doi: 10.1038/s43587-024-00588-1. Epub 2024 Mar 19. Nat Aging. 2024. PMID: 38503993
Kidney organoid models reveal cilium-autophagy metabolic axis as a therapeutic target for PKD both in vitro and in vivo.
Liu M, Zhang C, Gong X, Zhang T, Lian MM, Chew EGY, Cardilla A, Suzuki K, Wang H, Yuan Y, Li Y, Naik MY, Wang Y, Zhou B, Soon WZ, Aizawa E, Li P, Low JH, Tandiono M, Montagud E, Moya-Rull D, Rodriguez Esteban C, Luque Y, Fang M, Khor CC, Montserrat N, Campistol JM, Izpisua Belmonte JC, Foo JN, Xia Y. Liu M, et al. Among authors: izpisua belmonte jc. Cell Stem Cell. 2024 Jan 4;31(1):52-70.e8. doi: 10.1016/j.stem.2023.12.003. Cell Stem Cell. 2024. PMID: 38181751
Nuclear lamina erosion-induced resurrection of endogenous retroviruses underlies neuronal aging.
Zhang H, Li J, Yu Y, Ren J, Liu Q, Bao Z, Sun S, Liu X, Ma S, Liu Z, Yan K, Wu Z, Fan Y, Sun X, Zhang Y, Ji Q, Cheng F, Wei PH, Ma X, Zhang S, Xie Z, Niu Y, Wang YJ, Han JJ, Jiang T, Zhao G, Ji W, Izpisua Belmonte JC, Wang S, Qu J, Zhang W, Liu GH. Zhang H, et al. Among authors: izpisua belmonte jc. Cell Rep. 2023 Nov 28;42(11):113396. doi: 10.1016/j.celrep.2023.113396. Epub 2023 Oct 31. Cell Rep. 2023. PMID: 37910499 Free article. No abstract available.
Decoding aging-dependent regenerative decline across tissues at single-cell resolution.
Cai Y, Xiong M, Xin Z, Liu C, Ren J, Yang X, Lei J, Li W, Liu F, Chu Q, Zhang Y, Yin J, Ye Y, Liu D, Fan Y, Sun S, Jing Y, Zhao Q, Zhao L, Che S, Zheng Y, Yan H, Ma S, Wang S, Izpisua Belmonte JC, Qu J, Zhang W, Liu GH. Cai Y, et al. Among authors: izpisua belmonte jc. Cell Stem Cell. 2023 Dec 7;30(12):1674-1691.e8. doi: 10.1016/j.stem.2023.09.014. Epub 2023 Oct 27. Cell Stem Cell. 2023. PMID: 37898124
Author Correction: Universal DNA methylation age across mammalian tissues.
Lu AT, Fei Z, Haghani A, Robeck TR, Zoller JA, Li CZ, Lowe R, Yan Q, Zhang J, Vu H, Ablaeva J, Acosta-Rodriguez VA, Adams DM, Almunia J, Aloysius A, Ardehali R, Arneson A, Baker CS, Banks G, Belov K, Bennett NC, Black P, Blumstein DT, Bors EK, Breeze CE, Brooke RT, Brown JL, Carter GG, Caulton A, Cavin JM, Chakrabarti L, Chatzistamou I, Chen H, Cheng K, Chiavellini P, Choi OW, Clarke SM, Cooper LN, Cossette ML, Day J, DeYoung J, DiRocco S, Dold C, Ehmke EE, Emmons CK, Emmrich S, Erbay E, Erlacher-Reid C, Faulkes CG, Ferguson SH, Finno CJ, Flower JE, Gaillard JM, Garde E, Gerber L, Gladyshev VN, Gorbunova V, Goya RG, Grant MJ, Green CB, Hales EN, Hanson MB, Hart DW, Haulena M, Herrick K, Hogan AN, Hogg CJ, Hore TA, Huang T, Izpisua Belmonte JC, Jasinska AJ, Jones G, Jourdain E, Kashpur O, Katcher H, Katsumata E, Kaza V, Kiaris H, Kobor MS, Kordowitzki P, Koski WR, Krützen M, Kwon SB, Larison B, Lee SG, Lehmann M, Lemaitre JF, Levine AJ, Li C, Li X, Lim AR, Lin DTS, Lindemann DM, Little TJ, Macoretta N, Maddox D, Matkin CO, Mattison JA, McClure M, Mergl J, Meudt JJ, Montano GA, Mozhui K, Munshi-South J, Naderi A, Nagy M, Narayan P, Nathanielsz PW, Nguyen NB, Niehrs C, O'Brien… See abstract for full author list ➔ Lu AT, et al. Among authors: izpisua belmonte jc. Nat Aging. 2023 Nov;3(11):1462. doi: 10.1038/s43587-023-00499-7. Nat Aging. 2023. PMID: 37674040 Free PMC article. No abstract available.
430 results