Yoshinaka Y - Search Results

1

[Irritative effects of acemetacin and indomethacin on the gastrointestinal tracts of rats (author's transl)].

Nakamura M, Yoshinaka Y, Suzuki H, Wada Y. Nakamura M, et al. Among authors: yoshinaka y. Nihon Yakurigaku Zasshi. 1981 Nov;78(5):511-9. doi: 10.1254/fpj.78.511. Nihon Yakurigaku Zasshi. 1981. PMID: 7327463 Japanese.

2

Triglyceride-lowering effect of pitavastatin [corrected] in a rat model of postprandial lipemia.

Aoki T, Yoshinaka Y, Yamazaki H, Suzuki H, Tamaki T, Sato F, Kitahara M, Saito Y. Aoki T, et al. Among authors: yoshinaka y. Eur J Pharmacol. 2002 May 24;444(1-2):107-13. doi: 10.1016/s0014-2999(02)01547-9. Eur J Pharmacol. 2002. PMID: 12191589

3

Direct evidence for pitavastatin induced chromatin structure change in the KLF4 gene in endothelial cells.

Maejima T, Inoue T, Kanki Y, Kohro T, Li G, Ohta Y, Kimura H, Kobayashi M, Taguchi A, Tsutsumi S, Iwanari H, Yamamoto S, Aruga H, Dong S, Stevens JF, Poh HM, Yamamoto K, Kawamura T, Mimura I, Suehiro J, Sugiyama A, Kaneki K, Shibata H, Yoshinaka Y, Doi T, Asanuma A, Tanabe S, Tanaka T, Minami T, Hamakubo T, Sakai J, Nozaki N, Aburatani H, Nangaku M, Ruan X, Tanabe H, Ruan Y, Ihara S, Endo A, Kodama T, Wada Y. Maejima T, et al. Among authors: yoshinaka y. PLoS One. 2014 May 5;9(5):e96005. doi: 10.1371/journal.pone.0096005. eCollection 2014. PLoS One. 2014. PMID: 24797675 Free PMC article.

4

Pitavastatin increases ABCA1 expression by dual mechanisms: SREBP2-driven transcriptional activation and PPARα-dependent protein stabilization but without activating LXR in rat hepatoma McARH7777 cells.

Maejima T, Sugano T, Yamazaki H, Yoshinaka Y, Doi T, Tanabe S, Nishimaki-Mogami T. Maejima T, et al. Among authors: yoshinaka y. J Pharmacol Sci. 2011;116(1):107-15. doi: 10.1254/jphs.10241fp. Epub 2011 Apr 27. J Pharmacol Sci. 2011. PMID: 21521932 Free article.

5

A selective ACAT-1 inhibitor, K-604, suppresses fatty streak lesions in fat-fed hamsters without affecting plasma cholesterol levels.

Ikenoya M, Yoshinaka Y, Kobayashi H, Kawamine K, Shibuya K, Sato F, Sawanobori K, Watanabe T, Miyazaki A. Ikenoya M, et al. Among authors: yoshinaka y. Atherosclerosis. 2007 Apr;191(2):290-7. doi: 10.1016/j.atherosclerosis.2006.05.048. Epub 2006 Jul 3. Atherosclerosis. 2007. PMID: 16820149

6

A selective ACAT-1 inhibitor, K-604, stimulates collagen production in cultured smooth muscle cells and alters plaque phenotype in apolipoprotein E-knockout mice.

Yoshinaka Y, Shibata H, Kobayashi H, Kuriyama H, Shibuya K, Tanabe S, Watanabe T, Miyazaki A. Yoshinaka Y, et al. Atherosclerosis. 2010 Nov;213(1):85-91. doi: 10.1016/j.atherosclerosis.2010.08.048. Epub 2010 Aug 19. Atherosclerosis. 2010. PMID: 20843517

7

Mechanism of lipid-lowering action of the dipeptidyl peptidase-4 inhibitor, anagliptin, in low-density lipoprotein receptor-deficient mice.

Yano W, Inoue N, Ito S, Itou T, Yasumura M, Yoshinaka Y, Hagita S, Goto M, Nakagawa T, Inoue K, Tanabe S, Kaku K. Yano W, et al. Among authors: yoshinaka y. J Diabetes Investig. 2017 Mar;8(2):155-160. doi: 10.1111/jdi.12593. Epub 2016 Dec 15. J Diabetes Investig. 2017. PMID: 27860391 Free PMC article.

8

Design, synthesis and pharmacology of aortic-selective acyl-CoA: Cholesterol O-acyltransferase (ACAT/SOAT) inhibitors.

Shibuya K, Kawamine K, Miura T, Ozaki C, Edano T, Mizuno K, Yoshinaka Y, Tsunenari Y. Shibuya K, et al. Among authors: yoshinaka y. Bioorg Med Chem. 2018 Aug 7;26(14):4001-4013. doi: 10.1016/j.bmc.2018.06.024. Epub 2018 Jun 19. Bioorg Med Chem. 2018. PMID: 29945757

9

Discovery of Clinical Candidate 2-(4-(2-((1 H-Benzo[ d]imidazol-2-yl)thio)ethyl)piperazin-1-yl)- N-(6-methyl-2,4-bis(methylthio)pyridin-3-yl)acetamide Hydrochloride [K-604], an Aqueous-Soluble Acyl-CoA:Cholesterol O-Acyltransferase-1 Inhibitor.

Shibuya K, Kawamine K, Ozaki C, Ohgiya T, Edano T, Yoshinaka Y, Tsunenari Y. Shibuya K, et al. Among authors: yoshinaka y. J Med Chem. 2018 Dec 13;61(23):10635-10650. doi: 10.1021/acs.jmedchem.8b01256. Epub 2018 Nov 29. J Med Chem. 2018. PMID: 30433781

10

Machine learning-based muscle mass estimation using gait parameters in community-dwelling older adults: A cross-sectional study.

Fujita K, Hiyama T, Wada K, Aihara T, Matsumura Y, Hamatsuka T, Yoshinaka Y, Kimura M, Kuzuya M. Fujita K, et al. Among authors: yoshinaka y. Arch Gerontol Geriatr. 2022 Nov-Dec;103:104793. doi: 10.1016/j.archger.2022.104793. Epub 2022 Aug 14. Arch Gerontol Geriatr. 2022. PMID: 35987032

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