Batley B - Search Results

1

Exploring the binding preferences/specificity in the active site of human cathepsin E.

Rao-Naik C, Guruprasad K, Batley B, Rapundalo S, Hill J, Blundell T, Kay J, Dunn BM. Rao-Naik C, et al. Among authors: batley b. Proteins. 1995 Jun;22(2):168-81. doi: 10.1002/prot.340220209. Proteins. 1995. PMID: 7567964

2

Structure-function database for active site binding to the aspartic proteinases.

Rao C, Scarborough PE, Lowther WT, Kay J, Batley B, Rapundalo S, Klutchko S, Taylor MD, Dunn BM. Rao C, et al. Among authors: batley b. Adv Exp Med Biol. 1991;306:143-7. doi: 10.1007/978-1-4684-6012-4_19. Adv Exp Med Biol. 1991. PMID: 1812702 No abstract available.

3

Specificity in the binding of inhibitors to the active site of human/primate aspartic proteinases: analysis of P2-P1-P1'-P2' variation.

Rao CM, Scarborough PE, Kay J, Batley B, Rapundalo S, Klutchko S, Taylor MD, Lunney EA, Humblet CC, Dunn BM. Rao CM, et al. Among authors: batley b. J Med Chem. 1993 Sep 3;36(18):2614-20. doi: 10.1021/jm00070a004. J Med Chem. 1993. PMID: 8410973

4

Nonpeptidic potent HIV-1 protease inhibitors: (4-hydroxy-6-phenyl-2-oxo-2H- pyran-3-yl)thiomethanes that span P1-P2' subsites in a unique mode of active site binding.

Prasad JV, Para KS, Tummino PJ, Ferguson D, McQuade TJ, Lunney EA, Rapundalo ST, Batley BL, Hingorani G, Domagala JM, et al. Prasad JV, et al. Among authors: batley bl. J Med Chem. 1995 Mar 17;38(6):898-905. doi: 10.1021/jm00006a007. J Med Chem. 1995. PMID: 7699705

5

Design and synthesis of potent, selective, and orally active fluorine-containing renin inhibitors.

Doherty AM, Sircar I, Kornberg BE, Quin J 3rd, Winters RT, Kaltenbronn JS, Taylor MD, Batley BL, Rapundalo SR, Ryan MJ, et al. Doherty AM, et al. Among authors: batley bl. J Med Chem. 1992 Jan;35(1):2-14. doi: 10.1021/jm00079a001. J Med Chem. 1992. PMID: 1732531

6

Effect of an orally active renin inhibitor Cl-992 on blood pressure in normotensive and hypertensive monkeys.

Ryan MJ, Hicks GW, Batley BL, Rapundalo ST, Patt WC, Taylor DG, Keiser JA. Ryan MJ, et al. Among authors: batley bl. J Pharmacol Exp Ther. 1994 Jan;268(1):372-9. J Pharmacol Exp Ther. 1994. PMID: 8301578

7

Disparity between blood pressure and PRA inhibition after administration of a renin inhibitor to anesthetized dogs: methodological considerations.

Palmer RK, Rapundalo ST, Batley BL, Barnes AE, Singh S, Ryan MJ, Taylor DG Jr. Palmer RK, et al. Among authors: batley bl. Clin Exp Hypertens. 1993 Jul;15(4):663-81. doi: 10.3109/10641969309041636. Clin Exp Hypertens. 1993. PMID: 8374609

8

Soluble 2-substituted aminopyrido[2,3-d]pyrimidin-7-yl ureas. Structure-activity relationships against selected tyrosine kinases and exploration of in vitro and in vivo anticancer activity.

Schroeder MC, Hamby JM, Connolly CJ, Grohar PJ, Winters RT, Barvian MR, Moore CW, Boushelle SL, Crean SM, Kraker AJ, Driscoll DL, Vincent PW, Elliott WL, Lu GH, Batley BL, Dahring TK, Major TC, Panek RL, Doherty AM, Showalter HD. Schroeder MC, et al. Among authors: batley bl. J Med Chem. 2001 Jun 7;44(12):1915-26. doi: 10.1021/jm0004291. J Med Chem. 2001. PMID: 11384237

9

Inhibition of FGF-1 receptor tyrosine kinase activity by PD 161570, a new protein-tyrosine kinase inhibitor.

Batley BL, Doherty AM, Hamby JM, Lu GH, Keller P, Dahring TK, Hwang O, Crickard K, Panek RL. Batley BL, et al. Life Sci. 1998;62(2):143-50. doi: 10.1016/s0024-3205(97)01060-6. Life Sci. 1998. PMID: 9488112

10

In vitro pharmacological characterization of PD 166285, a new nanomolar potent and broadly active protein tyrosine kinase inhibitor.

Panek RL, Lu GH, Klutchko SR, Batley BL, Dahring TK, Hamby JM, Hallak H, Doherty AM, Keiser JA. Panek RL, et al. Among authors: batley bl. J Pharmacol Exp Ther. 1997 Dec;283(3):1433-44. J Pharmacol Exp Ther. 1997. PMID: 9400019

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