Bukhtiyarova M - Search Results

1

A continuous fluorescence-based assay of human cytomegalovirus protease using a peptide substrate.

Holskin BP, Bukhtiyarova M, Dunn BM, Baur P, de Chastonay J, Pennington MW. Holskin BP, et al. Among authors: bukhtiyarova m. Anal Biochem. 1995 May 1;227(1):148-55. doi: 10.1006/abio.1995.1264. Anal Biochem. 1995. PMID: 7668375

2

Comparison of the specificity of the aspartic proteinases towards internally consistent sets of oligopeptide substrates.

Dunn BM, Oda K, Kay J, Rao-Naik C, Lowther WT, Beyer BM, Scarborough PE, Bukhtiyarova M. Dunn BM, et al. Among authors: bukhtiyarova m. Adv Exp Med Biol. 1998;436:133-8. doi: 10.1007/978-1-4615-5373-1_18. Adv Exp Med Biol. 1998. PMID: 9561210 Review. No abstract available.

3

Detailed analysis of human cathepsin E prime region specificity.

Bukhtiyarova M, Rao-Naik C, Tatnell PJ, White PC, Kay J, Dunn BM. Bukhtiyarova M, et al. Adv Exp Med Biol. 1998;436:219-22. doi: 10.1007/978-1-4615-5373-1_31. Adv Exp Med Biol. 1998. PMID: 9561223 No abstract available.

4

Mutagenesis of p38alpha MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-OUT state.

Bukhtiyarova M, Karpusas M, Northrop K, Namboodiri HV, Springman EB. Bukhtiyarova M, et al. Biochemistry. 2007 May 15;46(19):5687-96. doi: 10.1021/bi0622221. Epub 2007 Apr 19. Biochemistry. 2007. PMID: 17441692

5

A Biacore biosensor method for detailed kinetic binding analysis of small molecule inhibitors of p38alpha mitogen-activated protein kinase.

Casper D, Bukhtiyarova M, Springman EB. Casper D, et al. Among authors: bukhtiyarova m. Anal Biochem. 2004 Feb 1;325(1):126-36. doi: 10.1016/j.ab.2003.10.025. Anal Biochem. 2004. PMID: 14715293

6

Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases.

Namboodiri HV, Bukhtiyarova M, Ramcharan J, Karpusas M, Lee Y, Springman EB. Namboodiri HV, et al. Among authors: bukhtiyarova m. Biochemistry. 2010 May 4;49(17):3611-8. doi: 10.1021/bi100070r. Biochemistry. 2010. PMID: 20337484

7

Improved expression, purification, and crystallization of p38alpha MAP kinase.

Bukhtiyarova M, Northrop K, Chai X, Casper D, Karpusas M, Springman E. Bukhtiyarova M, et al. Protein Expr Purif. 2004 Sep;37(1):154-61. doi: 10.1016/j.pep.2004.05.017. Protein Expr Purif. 2004. PMID: 15294293

8

Two classes of p38alpha MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes.

Michelotti EL, Moffett KK, Nguyen D, Kelly MJ, Shetty R, Chai X, Northrop K, Namboodiri V, Campbell B, Flynn GA, Fujimoto T, Hollinger FP, Bukhtiyarova M, Springman EB, Karpusas M. Michelotti EL, et al. Among authors: bukhtiyarova m. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5274-9. doi: 10.1016/j.bmcl.2005.08.038. Epub 2005 Sep 19. Bioorg Med Chem Lett. 2005. PMID: 16169718

9

Structure-based design of substituted biphenyl ethylene ethers as ligands binding in the hydrophobic pocket of gp41 and blocking the helical bundle formation.

Liu B, Joseph RW, Dorsey BD, Schiksnis RA, Northrop K, Bukhtiyarova M, Springman EB. Liu B, et al. Among authors: bukhtiyarova m. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5693-7. doi: 10.1016/j.bmcl.2009.08.018. Epub 2009 Aug 8. Bioorg Med Chem Lett. 2009. PMID: 19699090

10

Discovery and SAR of a series of 4,6-diamino-1,3,5-triazin-2-ol as novel non-nucleoside reverse transcriptase inhibitors of HIV-1.

Liu B, Lee Y, Zou J, Petrassi HM, Joseph RW, Chao W, Michelotti EL, Bukhtiyarova M, Springman EB, Dorsey BD. Liu B, et al. Among authors: bukhtiyarova m. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6592-6. doi: 10.1016/j.bmcl.2010.09.034. Epub 2010 Sep 21. Bioorg Med Chem Lett. 2010. PMID: 20888224

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