Holskin BP - Search Results

1

A continuous fluorescence-based assay of human cytomegalovirus protease using a peptide substrate.

Holskin BP, Bukhtiyarova M, Dunn BM, Baur P, de Chastonay J, Pennington MW. Holskin BP, et al. Anal Biochem. 1995 May 1;227(1):148-55. doi: 10.1006/abio.1995.1264. Anal Biochem. 1995. PMID: 7668375

2

Phosphoregulation of mixed-lineage kinase 1 activity by multiple phosphorylation in the activation loop.

Durkin JT, Holskin BP, Kopec KK, Reed MS, Spais CM, Steffy BM, Gessner G, Angeles TS, Pohl J, Ator MA, Meyer SL. Durkin JT, et al. Among authors: holskin bp. Biochemistry. 2004 Dec 28;43(51):16348-55. doi: 10.1021/bi049866y. Biochemistry. 2004. PMID: 15610029

3

ALK mutants in the kinase domain exhibit altered kinase activity and differential sensitivity to small molecule ALK inhibitors.

Lu L, Ghose AK, Quail MR, Albom MS, Durkin JT, Holskin BP, Angeles TS, Meyer SL, Ruggeri BA, Cheng M. Lu L, et al. Among authors: holskin bp. Biochemistry. 2009 Apr 28;48(16):3600-9. doi: 10.1021/bi8020923. Biochemistry. 2009. PMID: 19249873

4

Preliminary X-ray crystallography studies of recombinant human interleukin-1 alpha. Purification and structural characterization.

Hassell AM, Johanson KO, Goodhart P, Young PR, Holskin BP, Carr SA, Roberts GD, Simon PL, Chen MJ, Lewis M. Hassell AM, et al. Among authors: holskin bp. J Biol Chem. 1989 Mar 25;264(9):4948-52. J Biol Chem. 1989. PMID: 2784440 Free article.

5

Aequorin functional assay for characterization of G-protein-coupled receptors: implementation with cryopreserved transiently transfected cells.

Jones B, Holskin B, Meyer S, Ung T, Dupriez V, Flores SY, Burgeon E, Ator M, Duzic E. Jones B, et al. Anal Biochem. 2010 May 15;400(2):184-9. doi: 10.1016/j.ab.2010.01.028. Epub 2010 Jan 28. Anal Biochem. 2010. PMID: 20109436

6

Mixed-lineage kinase 1 and mixed-lineage kinase 3 subtype-selective dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: optimization, mixed-lineage kinase 1 crystallography, and oral in vivo activity in 1-methyl-4-phenyltetrahydropyridine models.

Hudkins RL, Diebold JL, Tao M, Josef KA, Park CH, Angeles TS, Aimone LD, Husten J, Ator MA, Meyer SL, Holskin BP, Durkin JT, Fedorov AA, Fedorov EV, Almo SC, Mathiasen JR, Bozyczko-Coyne D, Saporito MS, Scott RW, Mallamo JP. Hudkins RL, et al. Among authors: holskin bp. J Med Chem. 2008 Sep 25;51(18):5680-9. doi: 10.1021/jm8005838. Epub 2008 Aug 21. J Med Chem. 2008. PMID: 18714982

7

Modification of CellSensor irf1-bla TF-1 and irf1-bla HEL assays for direct comparison of wild-type JAK2 and JAK2 V617F inhibition.

Mason JL, Holskin BP, Murray KA, Meyer SL, Wells-Knecht KJ, Ator MA, Angeles TS. Mason JL, et al. Among authors: holskin bp. Assay Drug Dev Technol. 2011 Jun;9(3):311-8. doi: 10.1089/adt.2010.0297. Epub 2010 Dec 6. Assay Drug Dev Technol. 2011. PMID: 21133674

8

Comparison of two homogeneous cell-based kinase assays for JAK2 V617F: SureFire pSTAT5 and GeneBLAzer fluorescence resonance energy transfer assays.

Qian J, Mason JL, Holskin BP, Murray KA, Meyer SL, Ator MA, Angeles TS. Qian J, et al. Among authors: holskin bp. Assay Drug Dev Technol. 2012 Apr;10(2):212-7. doi: 10.1089/adt.2011.0399. Epub 2011 Dec 1. Assay Drug Dev Technol. 2012. PMID: 22132729

9

Anaplastic lymphoma kinase activity is essential for the proliferation and survival of anaplastic large-cell lymphoma cells.

Wan W, Albom MS, Lu L, Quail MR, Becknell NC, Weinberg LR, Reddy DR, Holskin BP, Angeles TS, Underiner TL, Meyer SL, Hudkins RL, Dorsey BD, Ator MA, Ruggeri BA, Cheng M. Wan W, et al. Among authors: holskin bp. Blood. 2006 Feb 15;107(4):1617-23. doi: 10.1182/blood-2005-08-3254. Epub 2005 Oct 27. Blood. 2006. PMID: 16254137 Free article.

10

Novel brain penetrant benzofuropiperidine 5-HT₆ receptor antagonists.

Sundar BG, Bailey TR, Dunn DD, Bacon ER, Salvino JM, Morton GC, Aimone LD, Zeqi H, Mathiasen JR, Dicamillo A, Huffman MJ, McKenna BA, Kopec K, Lu LD, Brown R, Qian J, Angeles T, Connors T, Spais C, Holskin B, Galinis D, Duzic E, Schaffhauser H, Rosse GC. Sundar BG, et al. Bioorg Med Chem Lett. 2012 Jan 1;22(1):120-3. doi: 10.1016/j.bmcl.2011.11.050. Epub 2011 Nov 22. Bioorg Med Chem Lett. 2012. PMID: 22153937

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