Brady EJ - Search Results

1

A novel insulin secretagogue is a phosphodiesterase inhibitor.

Leibowitz MD, Biswas C, Brady EJ, Conti M, Cullinan CA, Hayes NS, Manganiello VC, Saperstein R, Wang LH, Zafian PT, et al. Leibowitz MD, et al. Among authors: brady ej. Diabetes. 1995 Jan;44(1):67-74. doi: 10.2337/diab.44.1.67. Diabetes. 1995. PMID: 7813816

2

Glucose-dependent alterations of intracellular free calcium by glucagon-like peptide-1(7-36amide) in individual ob/ob mouse beta-cells.

Cullinan CA, Brady EJ, Saperstein R, Leibowitz MD. Cullinan CA, et al. Among authors: brady ej. Cell Calcium. 1994 May;15(5):391-400. doi: 10.1016/0143-4160(94)90014-0. Cell Calcium. 1994. PMID: 8033197

3

A novel glucagon receptor antagonist inhibits glucagon-mediated biological effects.

Qureshi SA, Rios Candelore M, Xie D, Yang X, Tota LM, Ding VD, Li Z, Bansal A, Miller C, Cohen SM, Jiang G, Brady E, Saperstein R, Duffy JL, Tata JR, Chapman KT, Moller DE, Zhang BB. Qureshi SA, et al. Diabetes. 2004 Dec;53(12):3267-73. doi: 10.2337/diabetes.53.12.3267. Diabetes. 2004. PMID: 15561959

4

Discovery and investigation of a novel class of thiophene-derived antagonists of the human glucagon receptor.

Duffy JL, Kirk BA, Konteatis Z, Campbell EL, Liang R, Brady EJ, Candelore MR, Ding VD, Jiang G, Liu F, Qureshi SA, Saperstein R, Szalkowski D, Tong S, Tota LM, Xie D, Yang X, Zafian P, Zheng S, Chapman KT, Zhang BB, Tata JR. Duffy JL, et al. Among authors: brady ej. Bioorg Med Chem Lett. 2005 Mar 1;15(5):1401-5. doi: 10.1016/j.bmcl.2005.01.003. Bioorg Med Chem Lett. 2005. PMID: 15713396

5

Design of a selective insulin receptor tyrosine kinase inhibitor and its effect on glucose uptake and metabolism in intact cells.

Saperstein R, Vicario PP, Strout HV, Brady E, Slater EE, Greenlee WJ, Ondeyka DL, Patchett AA, Hangauer DG. Saperstein R, et al. Biochemistry. 1989 Jun 27;28(13):5694-701. doi: 10.1021/bi00439a053. Biochemistry. 1989. PMID: 2550060

6

Effects of an alpha 2-adrenoceptor antagonist on glucose tolerance in the genetically obese mouse (C57BL/6J ob/ob).

Saperstein R, Chapin EW, Brady EJ, Slater EE. Saperstein R, et al. Among authors: brady ej. Metabolism. 1990 May;39(5):445-51. doi: 10.1016/0026-0495(90)90001-s. Metabolism. 1990. PMID: 1970847

7

Vanadate treatment of streptozotocin diabetic rats restores expression of the insulin-responsive glucose transporter in skeletal muscle.

Strout HV, Vicario PP, Biswas C, Saperstein R, Brady EJ, Pilch PF, Berger J. Strout HV, et al. Among authors: brady ej. Endocrinology. 1990 May;126(5):2728-32. doi: 10.1210/endo-126-5-2728. Endocrinology. 1990. PMID: 2184022

8

Beta(3)-adrenoceptor agonist-induced increases in lipolysis, metabolic rate, facial flushing, and reflex tachycardia in anesthetized rhesus monkeys.

Hom GJ, Forrest MJ, Bach TJ, Brady E, Candelore MR, Cascieri MA, Fletcher DJ, Fisher MH, Iliff SA, Mathvink R, Metzger J, Pecore V, Saperstein R, Shih T, Weber AE, Wyvratt M, Zafian P, MacIntyre DE. Hom GJ, et al. J Pharmacol Exp Ther. 2001 Apr;297(1):299-307. J Pharmacol Exp Ther. 2001. PMID: 11259557

9

Hepatic glucagon receptor binding and glucose-lowering in vivo by peptidyl and non-peptidyl glucagon receptor antagonists.

Dallas-Yang Q, Shen X, Strowski M, Brady E, Saperstein R, Gibson RE, Szalkowski D, Qureshi SA, Candelore MR, Fenyk-Melody JE, Parmee ER, Zhang BB, Jiang G. Dallas-Yang Q, et al. Eur J Pharmacol. 2004 Oct 6;501(1-3):225-34. doi: 10.1016/j.ejphar.2004.08.023. Eur J Pharmacol. 2004. PMID: 15464082

10

Activation of insulin signal transduction pathway and anti-diabetic activity of small molecule insulin receptor activators.

Qureshi SA, Ding V, Li Z, Szalkowski D, Biazzo-Ashnault DE, Xie D, Saperstein R, Brady E, Huskey S, Shen X, Liu K, Xu L, Salituro GM, Heck JV, Moller DE, Jones AB, Zhang BB. Qureshi SA, et al. J Biol Chem. 2000 Nov 24;275(47):36590-5. doi: 10.1074/jbc.M006287200. J Biol Chem. 2000. PMID: 10967116 Free article.

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