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A novel insulin secretagogue is a phosphodiesterase inhibitor.
Leibowitz MD, Biswas C, Brady EJ, Conti M, Cullinan CA, Hayes NS, Manganiello VC, Saperstein R, Wang LH, Zafian PT, et al. Leibowitz MD, et al. Diabetes. 1995 Jan;44(1):67-74. doi: 10.2337/diab.44.1.67. Diabetes. 1995. PMID: 7813816
Novel peroxisome proliferator-activated receptor (PPAR) gamma and PPARdelta ligands produce distinct biological effects.
Berger J, Leibowitz MD, Doebber TW, Elbrecht A, Zhang B, Zhou G, Biswas C, Cullinan CA, Hayes NS, Li Y, Tanen M, Ventre J, Wu MS, Berger GD, Mosley R, Marquis R, Santini C, Sahoo SP, Tolman RL, Smith RG, Moller DE. Berger J, et al. Among authors: leibowitz md. J Biol Chem. 1999 Mar 5;274(10):6718-25. doi: 10.1074/jbc.274.10.6718. J Biol Chem. 1999. PMID: 10037770 Free article.
Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice.
Zhang B, Graziano MP, Doebber TW, Leibowitz MD, White-Carrington S, Szalkowski DM, Hey PJ, Wu M, Cullinan CA, Bailey P, Lollmann B, Frederich R, Flier JS, Strader CD, Smith RG. Zhang B, et al. Among authors: leibowitz md. J Biol Chem. 1996 Apr 19;271(16):9455-9. doi: 10.1074/jbc.271.16.9455. J Biol Chem. 1996. PMID: 8621615 Free article.
Activation of PPARdelta alters lipid metabolism in db/db mice.
Leibowitz MD, Fiévet C, Hennuyer N, Peinado-Onsurbe J, Duez H, Bergera J, Cullinan CA, Sparrow CP, Baffic J, Berger GD, Santini C, Marquis RW, Tolman RL, Smith RG, Moller DE, Auwerx J. Leibowitz MD, et al. FEBS Lett. 2000 May 19;473(3):333-6. doi: 10.1016/s0014-5793(00)01554-4. FEBS Lett. 2000. PMID: 10818235 Free article.
Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor.
Claudel T, Leibowitz MD, Fiévet C, Tailleux A, Wagner B, Repa JJ, Torpier G, Lobaccaro JM, Paterniti JR, Mangelsdorf DJ, Heyman RA, Auwerx J. Claudel T, et al. Among authors: leibowitz md. Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2610-5. doi: 10.1073/pnas.041609298. Epub 2001 Feb 20. Proc Natl Acad Sci U S A. 2001. PMID: 11226287 Free PMC article.
Rosiglitazone induction of Insig-1 in white adipose tissue reveals a novel interplay of peroxisome proliferator-activated receptor gamma and sterol regulatory element-binding protein in the regulation of adipogenesis.
Kast-Woelbern HR, Dana SL, Cesario RM, Sun L, de Grandpre LY, Brooks ME, Osburn DL, Reifel-Miller A, Klausing K, Leibowitz MD. Kast-Woelbern HR, et al. Among authors: leibowitz md. J Biol Chem. 2004 Jun 4;279(23):23908-15. doi: 10.1074/jbc.M403145200. Epub 2004 Apr 8. J Biol Chem. 2004. PMID: 15073165 Free article.
39 results