Aristeromycin-5'-carboxaldehyde: a potent inhibitor of S-adenosyl-L-homocysteine hydrolase.
Liu S, Yuan CS, Borchardt RT.
Liu S, et al.
J Med Chem. 1996 Jun 7;39(12):2347-53. doi: 10.1021/jm950916u.
J Med Chem. 1996.
PMID: 8691429
In an earlier study, Liu et al. (Bioorg. Med. Chem. Lett. 1992, 2, 1741-1744) showed that both the E and Z isomers of 4',5'-didehydro-5'-fluoroaristeromycin were very potent irreversible inhibitors of S-adenosylhomocysteine (AdoHcy) hydrolase. ...However, Using 19F …
In an earlier study, Liu et al. (Bioorg. Med. Chem. Lett. 1992, 2, 1741-1744) showed that both the E and Z isomers of 4',5'-didehydro …