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A decrease in the intracellular guanosine 5'-triphosphate concentration is necessary for granulocytic differentiation of HL-60 cells, but growth cessation and differentiation are not associated with a change in the activation state of Ras, the transforming principle of HL-60 cells.
Pilz RB, Huvar I, Scheele JS, Van den Berghe G, Boss GR. Pilz RB, et al. Among authors: scheele js. Cell Growth Differ. 1997 Jan;8(1):53-9. Cell Growth Differ. 1997. PMID: 8993834
Signaling by small GTPases in the immune system.
Scheele JS, Marks RE, Boss GR. Scheele JS, et al. Immunol Rev. 2007 Aug;218:92-101. doi: 10.1111/j.1600-065X.2007.00530.x. Immunol Rev. 2007. PMID: 17624946 Review.
Determination of Ras-GTP and Ras-GDP in patients with acute myelogenous leukemia (AML), myeloproliferative syndrome (MPS), juvenile myelomonocytic leukemia (JMML), acute lymphocytic leukemia (ALL), and malignant lymphoma: assessment of mutational and indirect activation.
Raepple D, von Lintig F, Zemojtel T, Duchniewicz M, Jung A, Lübbert M, Boss GR, Scheele JS. Raepple D, et al. Among authors: scheele js. Ann Hematol. 2009 Apr;88(4):319-24. doi: 10.1007/s00277-008-0593-6. Epub 2008 Sep 11. Ann Hematol. 2009. PMID: 18784923 Free PMC article.
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