Neuberger MS - Search Results

1

Elements regulating somatic hypermutation of an immunoglobulin kappa gene: critical role for the intron enhancer/matrix attachment region.

Betz AG, Milstein C, González-Fernández A, Pannell R, Larson T, Neuberger MS. Betz AG, et al. Among authors: neuberger ms. Cell. 1994 Apr 22;77(2):239-48. doi: 10.1016/0092-8674(94)90316-6. Cell. 1994. PMID: 8168132

2

Lack of somatic mutation in a kappa light chain transgene.

Sharpe MJ, Neuberger M, Pannell R, Surani MA, Milstein C. Sharpe MJ, et al. Eur J Immunol. 1990 Jun;20(6):1379-85. doi: 10.1002/eji.1830200625. Eur J Immunol. 1990. PMID: 2115000

3

Somatic hypermutation.

Neuberger MS, Milstein C. Neuberger MS, et al. Curr Opin Immunol. 1995 Apr;7(2):248-54. doi: 10.1016/0952-7915(95)80010-7. Curr Opin Immunol. 1995. PMID: 7546385 Review.

4

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

Yélamos J, Klix N, Goyenechea B, Lozano F, Chui YL, González Fernández A, Pannell R, Neuberger MS, Milstein C. Yélamos J, et al. Among authors: neuberger ms. Nature. 1995 Jul 20;376(6537):225-9. doi: 10.1038/376225a0. Nature. 1995. PMID: 7617031

5

Somatic mutation of immunoglobulin lambda chains: a segment of the major intron hypermutates as much as the complementarity-determining regions.

González-Fernández A, Gupta SK, Pannell R, Neuberger MS, Milstein C. González-Fernández A, et al. Among authors: neuberger ms. Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12614-8. doi: 10.1073/pnas.91.26.12614. Proc Natl Acad Sci U S A. 1994. PMID: 7809087 Free PMC article.

6

Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes.

Betz AG, Neuberger MS, Milstein C. Betz AG, et al. Among authors: neuberger ms. Immunol Today. 1993 Aug;14(8):405-11. doi: 10.1016/0167-5699(93)90144-a. Immunol Today. 1993. PMID: 8397780 Review.

7

Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots.

Betz AG, Rada C, Pannell R, Milstein C, Neuberger MS. Betz AG, et al. Among authors: neuberger ms. Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2385-8. doi: 10.1073/pnas.90.6.2385. Proc Natl Acad Sci U S A. 1993. PMID: 8460148 Free PMC article.

8

The targeting of somatic hypermutation.

Jolly CJ, Wagner SD, Rada C, Klix N, Milstein C, Neuberger MS. Jolly CJ, et al. Among authors: neuberger ms. Semin Immunol. 1996 Jun;8(3):159-68. doi: 10.1006/smim.1996.0020. Semin Immunol. 1996. PMID: 8738915 Review.

9

Cells strongly expressing Ig(kappa) transgenes show clonal recruitment of hypermutation: a role for both MAR and the enhancers.

Goyenechea B, Klix N, Yélamos J, Williams GT, Riddell A, Neuberger MS, Milstein C. Goyenechea B, et al. Among authors: neuberger ms. EMBO J. 1997 Jul 1;16(13):3987-94. doi: 10.1093/emboj/16.13.3987. EMBO J. 1997. PMID: 9233808 Free PMC article.

10

Monitoring and interpreting the intrinsic features of somatic hypermutation.

Neuberger MS, Ehrenstein MR, Klix N, Jolly CJ, Yélamos J, Rada C, Milstein C. Neuberger MS, et al. Immunol Rev. 1998 Apr;162:107-16. doi: 10.1111/j.1600-065x.1998.tb01434.x. Immunol Rev. 1998. PMID: 9602357 Review.

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