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Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation.
Tang J, Lobatto ME, Hassing L, van der Staay S, van Rijs SM, Calcagno C, Braza MS, Baxter S, Fay F, Sanchez-Gaytan BL, Duivenvoorden R, Sager H, Astudillo YM, Leong W, Ramachandran S, Storm G, Pérez-Medina C, Reiner T, Cormode DP, Strijkers GJ, Stroes ES, Swirski FK, Nahrendorf M, Fisher EA, Fayad ZA, Mulder WJ. Tang J, et al. Sci Adv. 2015 Apr;1(3):e1400223. doi: 10.1126/sciadv.1400223. Sci Adv. 2015. PMID: 26295063 Free PMC article.
Atherosclerotic plaque targeting mechanism of long-circulating nanoparticles established by multimodal imaging.
Lobatto ME, Calcagno C, Millon A, Senders ML, Fay F, Robson PM, Ramachandran S, Binderup T, Paridaans MP, Sensarn S, Rogalla S, Gordon RE, Cardoso L, Storm G, Metselaar JM, Contag CH, Stroes ES, Fayad ZA, Mulder WJ. Lobatto ME, et al. ACS Nano. 2015 Feb 24;9(2):1837-47. doi: 10.1021/nn506750r. Epub 2015 Jan 28. ACS Nano. 2015. PMID: 25619964 Free PMC article.
HDL-mimetic PLGA nanoparticle to target atherosclerosis plaque macrophages.
Sanchez-Gaytan BL, Fay F, Lobatto ME, Tang J, Ouimet M, Kim Y, van der Staay SE, van Rijs SM, Priem B, Zhang L, Fisher EA, Moore KJ, Langer R, Fayad ZA, Mulder WJ. Sanchez-Gaytan BL, et al. Bioconjug Chem. 2015 Mar 18;26(3):443-51. doi: 10.1021/bc500517k. Epub 2015 Feb 13. Bioconjug Chem. 2015. PMID: 25650634 Free PMC article.
Immune cell screening of a nanoparticle library improves atherosclerosis therapy.
Tang J, Baxter S, Menon A, Alaarg A, Sanchez-Gaytan BL, Fay F, Zhao Y, Ouimet M, Braza MS, Longo VA, Abdel-Atti D, Duivenvoorden R, Calcagno C, Storm G, Tsimikas S, Moore KJ, Swirski FK, Nahrendorf M, Fisher EA, Pérez-Medina C, Fayad ZA, Reiner T, Mulder WJ. Tang J, et al. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6731-E6740. doi: 10.1073/pnas.1609629113. Epub 2016 Oct 17. Proc Natl Acad Sci U S A. 2016. PMID: 27791119 Free PMC article.
Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease.
Keliher EJ, Ye YX, Wojtkiewicz GR, Aguirre AD, Tricot B, Senders ML, Groenen H, Fay F, Perez-Medina C, Calcagno C, Carlucci G, Reiner T, Sun Y, Courties G, Iwamoto Y, Kim HY, Wang C, Chen JW, Swirski FK, Wey HY, Hooker J, Fayad ZA, Mulder WJ, Weissleder R, Nahrendorf M. Keliher EJ, et al. Nat Commun. 2017 Jan 16;8:14064. doi: 10.1038/ncomms14064. Nat Commun. 2017. PMID: 28091604 Free PMC article.
Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis.
Beldman TJ, Senders ML, Alaarg A, Pérez-Medina C, Tang J, Zhao Y, Fay F, Deichmöller J, Born B, Desclos E, van der Wel NN, Hoebe RA, Kohen F, Kartvelishvily E, Neeman M, Reiner T, Calcagno C, Fayad ZA, de Winther MPJ, Lutgens E, Mulder WJM, Kluza E. Beldman TJ, et al. ACS Nano. 2017 Jun 27;11(6):5785-5799. doi: 10.1021/acsnano.7b01385. Epub 2017 May 15. ACS Nano. 2017. PMID: 28463501 Free PMC article.
Multimodal Positron Emission Tomography Imaging to Quantify Uptake of 89Zr-Labeled Liposomes in the Atherosclerotic Vessel Wall.
Lobatto ME, Binderup T, Robson PM, Giesen LFP, Calcagno C, Witjes J, Fay F, Baxter S, Wessel CH, Eldib M, Bini J, Carlin SD, Stroes ESG, Storm G, Kjaer A, Lewis JS, Reiner T, Fayad ZA, Mulder WJM, Pérez-Medina C. Lobatto ME, et al. Bioconjug Chem. 2020 Feb 19;31(2):360-368. doi: 10.1021/acs.bioconjchem.9b00256. Epub 2019 Jun 7. Bioconjug Chem. 2020. PMID: 31095372 Free PMC article.
137 results