Finke PE - Search Results

1

Mechanism of inhibition of human leucocyte elastase by monocyclic beta-lactams.

Chabin R, Green BG, Gale P, Maycock AL, Weston H, Dorn CP, Finke PE, Hagmann WK, Hale JJ, MacCoss M, et al. Chabin R, et al. Among authors: finke pe. Biochemistry. 1993 Aug 31;32(34):8970-80. doi: 10.1021/bi00085a031. Biochemistry. 1993. PMID: 8364042

2

PMN elastases: a comparison of the specificity of human isozymes and the enzyme from other species toward substrates and inhibitors.

Green BG, Weston H, Ashe BM, Doherty J, Finke P, Hagmann W, Lark M, Mao J, Maycock A, Moore V, et al. Green BG, et al. Arch Biochem Biophys. 1991 Apr;286(1):284-92. doi: 10.1016/0003-9861(91)90042-h. Arch Biochem Biophys. 1991. PMID: 1897955

3

Orally active beta-lactam inhibitors of human leukocyte elastase-1. Activity of 3,3-diethyl-2-azetidinones.

Shah SK, Dorn CP Jr, Finke PE, Hale JJ, Hagmann WK, Brause KA, Chandler GO, Kissinger AL, Ashe BM, Weston H, et al. Shah SK, et al. Among authors: finke pe. J Med Chem. 1992 Oct 16;35(21):3745-54. doi: 10.1021/jm00099a003. J Med Chem. 1992. PMID: 1433189

4

Specificity, stability, and potency of monocyclic beta-lactam inhibitors of human leucocyte elastase.

Knight WB, Green BG, Chabin RM, Gale P, Maycock AL, Weston H, Kuo DW, Westler WM, Dorn CP, Finke PE, et al. Knight WB, et al. Among authors: finke pe. Biochemistry. 1992 Sep 8;31(35):8160-70. doi: 10.1021/bi00150a007. Biochemistry. 1992. PMID: 1525156

5

Mechanism of inhibition of human leukocyte elastase by two cephalosporin derivatives.

Knight WB, Maycock AL, Green BG, Ashe BM, Gale P, Weston H, Finke PE, Hagmann WK, Shah SK, Doherty JB. Knight WB, et al. Among authors: finke pe. Biochemistry. 1992 Jun 2;31(21):4980-6. doi: 10.1021/bi00136a010. Biochemistry. 1992. PMID: 1599924

6

Inhibition of human leukocyte elastase. 2. Inhibition by substituted cephalosporin esters and amides.

Finke PE, Ashe BM, Knight WB, Maycock AL, Navia MA, Shah SK, Thompson KR, Underwood DJ, Weston H, Zimmerman M, et al. Finke PE, et al. J Med Chem. 1990 Sep;33(9):2522-8. doi: 10.1021/jm00171a029. J Med Chem. 1990. PMID: 2391692

7

Inhibition of human leukocyte elastase. 3. Synthesis and activity of 3'-substituted cephalosporins.

Shah SK, Brause KA, Chandler GO, Finke PE, Ashe BM, Weston H, Knight WB, Maycock AL, Doherty JB. Shah SK, et al. Among authors: finke pe. J Med Chem. 1990 Sep;33(9):2529-35. doi: 10.1021/jm00171a030. J Med Chem. 1990. PMID: 2391693

8

Mechanism of inhibition of human leucocyte elastase by beta-lactams. 3. Use of electrospray ionization mass spectrometry and two-dimensional NMR techniques to identify beta-lactam-derived E-I complexes.

Underwood DJ, Green BG, Chabin R, Mills S, Doherty JB, Finke PE, MacCoss M, Shah SK, Burgey CS, Dickinson TA, et al. Underwood DJ, et al. Among authors: finke pe. Biochemistry. 1995 Nov 7;34(44):14344-55. doi: 10.1021/bi00044a011. Biochemistry. 1995. PMID: 7578038

9

Orally active beta-lactam inhibitors of human leukocyte elastase. 3. Stereospecific synthesis and structure-activity relationships for 3,3-dialkylazetidin-2-ones.

Finke PE, Shah SK, Fletcher DS, Ashe BM, Brause KA, Chandler GO, Dellea PS, Hand KM, Maycock AL, Osinga DG, et al. Finke PE, et al. J Med Chem. 1995 Jun 23;38(13):2449-62. doi: 10.1021/jm00013a021. J Med Chem. 1995. PMID: 7608910

10

Chemical, biochemical, pharmacokinetic, and biological properties of L-680,833: a potent, orally active monocyclic beta-lactam inhibitor of human polymorphonuclear leukocyte elastase.

Doherty JB, Shah SK, Finke PE, Dorn CP Jr, Hagmann WK, Hale JJ, Kissinger AL, Thompson KR, Brause K, Chandler GO, et al. Doherty JB, et al. Among authors: finke pe. Proc Natl Acad Sci U S A. 1993 Sep 15;90(18):8727-31. doi: 10.1073/pnas.90.18.8727. Proc Natl Acad Sci U S A. 1993. PMID: 8378355 Free PMC article.

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