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Increased intracellular cyclic AMP inhibits inositol phospholipid hydrolysis induced by perturbation of the T cell receptor/CD3 complex but not by G-protein stimulation. Association with protein kinase A-mediated phosphorylation of phospholipase C-gamma 1.
Alava MA, DeBell KE, Conti A, Hoffman T, Bonvini E. Alava MA, et al. Among authors: bonvini e. Biochem J. 1992 May 15;284 ( Pt 1)(Pt 1):189-99. doi: 10.1042/bj2840189. Biochem J. 1992. PMID: 1318020 Free PMC article.
Costimulation of T cell receptor/CD3-mediated activation of resting human CD4+ T cells by leukocyte function-associated antigen-1 ligand intercellular cell adhesion molecule-1 involves prolonged inositol phospholipid hydrolysis and sustained increase of intracellular Ca2+ levels.
Van Seventer GA, Bonvini E, Yamada H, Conti A, Stringfellow S, June CH, Shaw S. Van Seventer GA, et al. Among authors: bonvini e. J Immunol. 1992 Dec 15;149(12):3872-80. J Immunol. 1992. PMID: 1360995
137 results