Lin PF - Search Results

1

Aminodiol HIV protease inhibitors. Synthesis and structure-activity relationships of P1/P1' compounds: correlation between lipophilicity and cytotoxicity.

Chen P, Cheng PT, Alam M, Beyer BD, Bisacchi GS, Dejneka T, Evans AJ, Greytok JA, Hermsmeier MA, Humphreys WG, Jacobs GA, Kocy O, Lin PF, Lis KA, Marella MA, Ryono DE, Sheaffer AK, Spergel SH, Sun CQ, Tino JA, Vite G, Colonno RJ, Zahler R, Barrish JC. Chen P, et al. Among authors: lin pf. J Med Chem. 1996 May 10;39(10):1991-2007. doi: 10.1021/jm950717a. J Med Chem. 1996. PMID: 8642558

2

Characterization of a human immunodeficiency virus type 1 variant with reduced sensitivity to an aminodiol protease inhibitor.

Patick AK, Rose R, Greytok J, Bechtold CM, Hermsmeier MA, Chen PT, Barrish JC, Zahler R, Colonno RJ, Lin PF. Patick AK, et al. Among authors: lin pf. J Virol. 1995 Apr;69(4):2148-52. doi: 10.1128/JVI.69.4.2148-2152.1995. J Virol. 1995. PMID: 7884862 Free PMC article.

3

Aminodiol HIV protease inhibitors. 1. Design, synthesis, and preliminary SAR.

Barrish JC, Gordon E, Alam M, Lin PF, Bisacchi GS, Chen P, Cheng PT, Fritz AW, Greytok JA, Hermsmeier MA. Barrish JC, et al. Among authors: lin pf. J Med Chem. 1994 Jun 10;37(12):1758-68. doi: 10.1021/jm00038a005. J Med Chem. 1994. PMID: 8021916

4

Substituted naphthalenones as a new structural class of HIV-1 reverse transcriptase inhibitors.

Alam M, Bechtold CM, Patick AK, Skoog MT, Gant TG, Colonno RJ, Meyers AI, Li H, Trimble J, Lin PF. Alam M, et al. Among authors: lin pf. Antiviral Res. 1993 Oct;22(2-3):131-41. doi: 10.1016/0166-3542(93)90091-v. Antiviral Res. 1993. PMID: 7506510

5

Human immunodeficiency virus type 1 viral background plays a major role in development of resistance to protease inhibitors.

Rose RE, Gong YF, Greytok JA, Bechtold CM, Terry BJ, Robinson BS, Alam M, Colonno RJ, Lin PF. Rose RE, et al. Among authors: lin pf. Proc Natl Acad Sci U S A. 1996 Feb 20;93(4):1648-53. doi: 10.1073/pnas.93.4.1648. Proc Natl Acad Sci U S A. 1996. PMID: 8643685 Free PMC article.

6

Evaluation of reverse transcriptase and protease inhibitors in two-drug combinations against human immunodeficiency virus replication.

Deminie CA, Bechtold CM, Stock D, Alam M, Djang F, Balch AH, Chou TC, Prichard M, Colonno RJ, Lin PF. Deminie CA, et al. Among authors: lin pf. Antimicrob Agents Chemother. 1996 Jun;40(6):1346-51. doi: 10.1128/AAC.40.6.1346. Antimicrob Agents Chemother. 1996. PMID: 8725999 Free PMC article.

7

In vitro resistance profile of the human immunodeficiency virus type 1 protease inhibitor BMS-232632.

Gong YF, Robinson BS, Rose RE, Deminie C, Spicer TP, Stock D, Colonno RJ, Lin PF. Gong YF, et al. Among authors: lin pf. Antimicrob Agents Chemother. 2000 Sep;44(9):2319-26. doi: 10.1128/AAC.44.9.2319-2326.2000. Antimicrob Agents Chemother. 2000. PMID: 10952574 Free PMC article.

8

Characterization of siamycin I, a human immunodeficiency virus fusion inhibitor.

Lin PF, Samanta H, Bechtold CM, Deminie CA, Patick AK, Alam M, Riccardi K, Rose RE, White RJ, Colonno RJ. Lin PF, et al. Antimicrob Agents Chemother. 1996 Jan;40(1):133-8. doi: 10.1128/AAC.40.1.133. Antimicrob Agents Chemother. 1996. PMID: 8787894 Free PMC article.

9

BMS-232632, a highly potent human immunodeficiency virus protease inhibitor that can be used in combination with other available antiretroviral agents.

Robinson BS, Riccardi KA, Gong YF, Guo Q, Stock DA, Blair WS, Terry BJ, Deminie CA, Djang F, Colonno RJ, Lin PF. Robinson BS, et al. Among authors: lin pf. Antimicrob Agents Chemother. 2000 Aug;44(8):2093-9. doi: 10.1128/AAC.44.8.2093-2099.2000. Antimicrob Agents Chemother. 2000. PMID: 10898681 Free PMC article.

10

Inhibitors of HIV-1 attachment. Part 8: the effect of C7-heteroaryl substitution on the potency, and in vitro and in vivo profiles of indole-based inhibitors.

Yeung KS, Qiu Z, Yin Z, Trehan A, Fang H, Pearce B, Yang Z, Zadjura L, D'Arienzo CJ, Riccardi K, Shi PY, Spicer TP, Gong YF, Browning MR, Hansel S, Santone K, Barker J, Coulter T, Lin PF, Meanwell NA, Kadow JF. Yeung KS, et al. Among authors: lin pf. Bioorg Med Chem Lett. 2013 Jan 1;23(1):203-8. doi: 10.1016/j.bmcl.2012.10.117. Epub 2012 Nov 5. Bioorg Med Chem Lett. 2013. PMID: 23200249

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