Dean DC - Search Results

1

A receptor in pituitary and hypothalamus that functions in growth hormone release.

Howard AD, Feighner SD, Cully DF, Arena JP, Liberator PA, Rosenblum CI, Hamelin M, Hreniuk DL, Palyha OC, Anderson J, Paress PS, Diaz C, Chou M, Liu KK, McKee KK, Pong SS, Chaung LY, Elbrecht A, Dashkevicz M, Heavens R, Rigby M, Sirinathsinghji DJ, Dean DC, Melillo DG, Patchett AA, Nargund R, Griffin PR, DeMartino JA, Gupta SK, Schaeffer JM, Smith RG, Van der Ploeg LH. Howard AD, et al. Among authors: dean dc. Science. 1996 Aug 16;273(5277):974-7. doi: 10.1126/science.273.5277.974. Science. 1996. PMID: 8688086

2

Development of a high specific activity sulfur-35-labeled sulfonamide radioligand that allowed the identification of a new growth hormone secretagogue receptor.

Dean DC, Nargund RP, Pong SS, Chaung LY, Griffin P, Melillo DG, Ellsworth RL, Van der Ploeg LH, Patchett AA, Smith RG. Dean DC, et al. J Med Chem. 1996 Apr 26;39(9):1767-70. doi: 10.1021/jm960054c. J Med Chem. 1996. PMID: 8627599 No abstract available.

3

Identification of a new G-protein-linked receptor for growth hormone secretagogues.

Pong SS, Chaung LY, Dean DC, Nargund RP, Patchett AA, Smith RG. Pong SS, et al. Among authors: dean dc. Mol Endocrinol. 1996 Jan;10(1):57-61. doi: 10.1210/mend.10.1.8838145. Mol Endocrinol. 1996. PMID: 8838145

4

Structural requirements for the activation of the human growth hormone secretagogue receptor by peptide and nonpeptide secretagogues.

Feighner SD, Howard AD, Prendergast K, Palyha OC, Hreniuk DL, Nargund R, Underwood D, Tata JR, Dean DC, Tan CP, McKee KK, Woods JW, Patchett AA, Smith RG, Van der Ploeg LH. Feighner SD, et al. Among authors: dean dc. Mol Endocrinol. 1998 Jan;12(1):137-45. doi: 10.1210/mend.12.1.0051. Mol Endocrinol. 1998. PMID: 9440817

5

Assessing and minimizing time-dependent inhibition of cytochrome P450 3A in drug discovery: a case study with melanocortin-4 receptor agonists.

Tang W, Stearns RA, Wang RW, Miller RR, Chen Q, Ngui J, Bakshi RK, Nargund RP, Dean DC, Baillie TA. Tang W, et al. Among authors: dean dc. Xenobiotica. 2008 Nov;38(11):1437-51. doi: 10.1080/00498250802464685. Xenobiotica. 2008. PMID: 18841517

6

Ivermectin and nodulisporic acid receptors in Drosophila melanogaster contain both gamma-aminobutyric acid-gated Rdl and glutamate-gated GluCl alpha chloride channel subunits.

Ludmerer SW, Warren VA, Williams BS, Zheng Y, Hunt DC, Ayer MB, Wallace MA, Chaudhary AG, Egan MA, Meinke PT, Dean DC, Garcia ML, Cully DF, Smith MM. Ludmerer SW, et al. Among authors: dean dc. Biochemistry. 2002 May 21;41(20):6548-60. doi: 10.1021/bi015920o. Biochemistry. 2002. PMID: 12009920

7

Synthesis of the first sulfur-35-labeled hERG radioligand.

Raab CE, Butcher JW, Connolly TM, Karczewski J, Yu NX, Staskiewicz SJ, Liverton N, Dean DC, Melillo DG. Raab CE, et al. Among authors: dean dc. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1692-5. doi: 10.1016/j.bmcl.2005.12.021. Epub 2006 Jan 11. Bioorg Med Chem Lett. 2006. PMID: 16377185

8

The absorption, distribution, metabolism and excretion of rofecoxib, a potent and selective cyclooxygenase-2 inhibitor, in rats and dogs.

Halpin RA, Geer LA, Zhang KE, Marks TM, Dean DC, Jones AN, Melillo D, Doss G, Vyas KP. Halpin RA, et al. Among authors: dean dc. Drug Metab Dispos. 2000 Oct;28(10):1244-54. Drug Metab Dispos. 2000. PMID: 10997947

9

Mechanistic studies on the reversible metabolism of rofecoxib to 5-hydroxyrofecoxib in the rat: evidence for transient ring opening of a substituted 2-furanone derivative using stable isotope-labeling techniques.

Baillie TA, Halpin RA, Matuszewski BK, Geer LA, Chavez-Eng CM, Dean D, Braun M, Doss G, Jones A, Marks T, Melillo D, Vyas KP. Baillie TA, et al. Drug Metab Dispos. 2001 Dec;29(12):1614-28. Drug Metab Dispos. 2001. PMID: 11717181

10

The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1).

Garcia-Calvo M, Lisnock J, Bull HG, Hawes BE, Burnett DA, Braun MP, Crona JH, Davis HR Jr, Dean DC, Detmers PA, Graziano MP, Hughes M, Macintyre DE, Ogawa A, O'neill KA, Iyer SP, Shevell DE, Smith MM, Tang YS, Makarewicz AM, Ujjainwalla F, Altmann SW, Chapman KT, Thornberry NA. Garcia-Calvo M, et al. Among authors: dean dc. Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8132-7. doi: 10.1073/pnas.0500269102. Epub 2005 May 31. Proc Natl Acad Sci U S A. 2005. PMID: 15928087 Free PMC article.

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