Björkhem I - Search Results

1

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation.

Lütjohann D, Breuer O, Ahlborg G, Nennesmo I, Sidén A, Diczfalusy U, Björkhem I. Lütjohann D, et al. Among authors: bjorkhem i. Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9799-804. doi: 10.1073/pnas.93.18.9799. Proc Natl Acad Sci U S A. 1996. PMID: 8790411 Free PMC article.

2

Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain.

Heverin M, Meaney S, Lütjohann D, Diczfalusy U, Wahren J, Björkhem I. Heverin M, et al. Among authors: bjorkhem i. J Lipid Res. 2005 May;46(5):1047-52. doi: 10.1194/jlr.M500024-JLR200. Epub 2005 Mar 1. J Lipid Res. 2005. PMID: 15741649 Free article.

3

Use of an 18O2 inhalation technique and mass isotopomer distribution analysis to study oxygenation of cholesterol in rat. Evidence for in vivo formation of 7-oxo-, 7 beta-hydroxy-, 24-hydroxy-, and 25-hydroxycholesterol.

Breuer O, Björkhem I. Breuer O, et al. Among authors: bjorkhem i. J Biol Chem. 1995 Sep 1;270(35):20278-84. doi: 10.1074/jbc.270.35.20278. J Biol Chem. 1995. PMID: 7657597 Free article.

4

Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages.

Björkhem I, Andersson O, Diczfalusy U, Sevastik B, Xiu RJ, Duan C, Lund E. Björkhem I, et al. Proc Natl Acad Sci U S A. 1994 Aug 30;91(18):8592-6. doi: 10.1073/pnas.91.18.8592. Proc Natl Acad Sci U S A. 1994. PMID: 8078928 Free PMC article.

5

Novel pathways for elimination of cholesterol by extrahepatic formation of side-chain oxidized oxysterols.

Diczfalusy U, Lund E, Lütjohann D, Björkhem I. Diczfalusy U, et al. Among authors: bjorkhem i. Scand J Clin Lab Invest Suppl. 1996;226:9-17. Scand J Clin Lab Invest Suppl. 1996. PMID: 8981665 Review.

6

Importance of a novel oxidative mechanism for elimination of brain cholesterol. Turnover of cholesterol and 24(S)-hydroxycholesterol in rat brain as measured with 18O2 techniques in vivo and in vitro.

Björkhem I, Lütjohann D, Breuer O, Sakinis A, Wennmalm A. Björkhem I, et al. J Biol Chem. 1997 Nov 28;272(48):30178-84. doi: 10.1074/jbc.272.48.30178. J Biol Chem. 1997. PMID: 9374499 Free article.

Very recently we showed that there is a continuous age-dependent flux of 24(S)-hydroxycholesterol from the human brain into the circulation (Lutjohann, D., Breuer, O., Ahlborg, G., Nennesmo, I., Siden, A., Diczfalusy, U., and Bjorkhem, I. (1996) Proc. Natl. . …

Very recently we showed that there is a continuous age-dependent flux of 24(S)-hydroxycholesterol from the human brain into the circulation …

7

Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation.

Björkhem I, Lütjohann D, Diczfalusy U, Ståhle L, Ahlborg G, Wahren J. Björkhem I, et al. J Lipid Res. 1998 Aug;39(8):1594-600. J Lipid Res. 1998. PMID: 9717719 Free article.

8

Elimination of cholesterol as cholestenoic acid in human lung by sterol 27-hydroxylase: evidence that most of this steroid in the circulation is of pulmonary origin.

Babiker A, Andersson O, Lindblom D, van der Linden J, Wiklund B, Lütjohann D, Diczfalusy U, Björkhem I. Babiker A, et al. Among authors: bjorkhem i. J Lipid Res. 1999 Aug;40(8):1417-25. J Lipid Res. 1999. PMID: 10428977 Free article.

9

Plasma levels of 24S-hydroxycholesterol reflect the balance between cerebral production and hepatic metabolism and are inversely related to body surface.

Bretillon L, Lütjohann D, Ståhle L, Widhe T, Bindl L, Eggertsen G, Diczfalusy U, Björkhem I. Bretillon L, et al. Among authors: bjorkhem i. J Lipid Res. 2000 May;41(5):840-5. J Lipid Res. 2000. PMID: 10787445 Free article.

10

Formation of oxysterols from different pools of cholesterol as studied by stable isotope technique: cerebral origin of most circulating 24S-hydroxycholesterol in rats, but not in mice.

Meaney S, Lütjohann D, Diczfalusy U, Björkhem I. Meaney S, et al. Among authors: bjorkhem i. Biochim Biophys Acta. 2000 Jul 19;1486(2-3):293-8. doi: 10.1016/s1388-1981(00)00070-6. Biochim Biophys Acta. 2000. PMID: 10903480

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