Chen H - Search Results

1

Growth hormone (GH) and insulin-like growth factor I responses after treatments with an orally active GH secretagogue L-163,255 in swine.

Chang CH, Rickes EL, McGuire L, Frazier E, Chen H, Barakat K, Nargund R, Patchett A, Smith RG, Hickey GJ. Chang CH, et al. Among authors: chen h. Endocrinology. 1996 Nov;137(11):4851-6. doi: 10.1210/endo.137.11.8895356. Endocrinology. 1996. PMID: 8895356

2

Mediation by the central nervous system is critical to the in vivo activity of the GH secretagogue L-692,585.

Hickey GJ, Drisko J, Faidley T, Chang C, Anderson LL, Nicolich S, McGuire L, Rickes E, Krupa D, Feeney W, Friscino B, Cunningham P, Frazier E, Chen H, Laroque P, Smith RG. Hickey GJ, et al. Among authors: chen h. J Endocrinol. 1996 Feb;148(2):371-80. doi: 10.1677/joe.0.1480371. J Endocrinol. 1996. PMID: 8699151

3

MK-0677, a potent, novel, orally active growth hormone (GH) secretagogue: GH, insulin-like growth factor I, and other hormonal responses in beagles.

Jacks T, Smith R, Judith F, Schleim K, Frazier E, Chen H, Krupa D, Hora D Jr, Nargund R, Patchett A, Hickey G. Jacks T, et al. Among authors: chen h. Endocrinology. 1996 Dec;137(12):5284-9. doi: 10.1210/endo.137.12.8940347. Endocrinology. 1996. PMID: 8940347

4

Increases in circulating insulin-like growth factor I levels by the oral growth hormone secretagogue MK-0677 in the beagle are dependent upon pituitary mediation.

Schleim KD, Jacks T, Cunningham P, Feeney W, Frazier EG, Niebauer GW, Zhang D, Chen H, Smith RG, Hickey G. Schleim KD, et al. Among authors: chen h. Endocrinology. 1999 Apr;140(4):1552-8. doi: 10.1210/endo.140.4.6667. Endocrinology. 1999. PMID: 10098487

5

Effects of acute and repeated intravenous administration of L-692,585, a novel non-peptidyl growth hormone secretagogue, on plasma growth hormone, IGF-1, ACTH, cortisol, prolactin, insulin, and thyroxine levels in beagles.

Jacks T, Hickey G, Judith F, Taylor J, Chen H, Krupa D, Feeney W, Schoen W, Ok D, Fisher M, et al. Jacks T, et al. Among authors: chen h. J Endocrinol. 1994 Nov;143(2):399-406. doi: 10.1677/joe.0.1430399. J Endocrinol. 1994. PMID: 7830002

6

Activity of a novel nonpeptidyl growth hormone secretagogue, L-700,653, in swine.

Chang CH, Rickes EL, Marsilio F, McGuire L, Cosgrove S, Taylor J, Chen H, Feighner S, Clark JN, De Vita R, et al. Chang CH, et al. Among authors: chen h. Endocrinology. 1995 Mar;136(3):1065-71. doi: 10.1210/endo.136.3.7867560. Endocrinology. 1995. PMID: 7867560

7

Discovery and activity of (1R,4S,6R)-N-[(1R)-2-[4-cyclohexyl-4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4-fluorophenyl)methyl]-2-oxoethyl]-2-methyl-2-azabicyclo[2.2.2]octane-6-carboxamide (3, RY764), a potent and selective melanocortin subtype-4 receptor agonist.

Ye Z, Guo L, Barakat KJ, Pollard PG, Palucki BL, Sebhat IK, Bakshi RK, Tang R, Kalyani RN, Vongs A, Chen AS, Chen HY, Rosenblum CI, MacNeil T, Weinberg DH, Peng Q, Tamvakopoulos C, Miller RR, Stearns RA, Cashen DE, Martin WJ, Metzger JM, Strack AM, MacIntyre DE, Van der Ploeg LH, Patchett AA, Wyvratt MJ, Nargund RP. Ye Z, et al. Among authors: chen hy, chen as. Bioorg Med Chem Lett. 2005 Aug 1;15(15):3501-5. doi: 10.1016/j.bmcl.2005.05.109. Bioorg Med Chem Lett. 2005. PMID: 15982875

8

Induction of neuropeptide Y expression in dorsomedial hypothalamus of diet-induced obese mice.

Guan XM, Yu H, Trumbauer M, Frazier E, Van der Ploeg LH, Chen H. Guan XM, et al. Among authors: chen h. Neuroreport. 1998 Oct 26;9(15):3415-9. doi: 10.1097/00001756-199810260-00015. Neuroreport. 1998. PMID: 9855291

9

Discovery of potent, selective, and orally bioavailable 3H-spiro[isobenzofuran-1,4'-piperidine] based melanocortin subtype-4 receptor agonists.

Guo L, Ye Z, Liu J, He S, Bakshi RK, Sebhat IK, Dobbelaar PH, Hong Q, Jian T, Dellureficio JP, Tsou NN, Ball RG, Weinberg DH, MacNeil T, Tang R, Tamvakopoulos C, Peng Q, Chen HY, Chen AS, Martin WJ, MacIntyre DE, Strack AM, Fong TM, Wyvratt MJ, Nargund RP. Guo L, et al. Among authors: chen hy, chen as. Bioorg Med Chem Lett. 2010 Aug 15;20(16):4895-900. doi: 10.1016/j.bmcl.2010.06.068. Epub 2010 Jun 17. Bioorg Med Chem Lett. 2010. PMID: 20621473

10

Utility of firefly luciferase as a reporter gene for promoter activity in transgenic mice.

DiLella AG, Hope DA, Chen H, Trumbauer M, Schwartz RJ, Smith RG. DiLella AG, et al. Among authors: chen h. Nucleic Acids Res. 1988 May 11;16(9):4159. doi: 10.1093/nar/16.9.4159. Nucleic Acids Res. 1988. PMID: 3375079 Free PMC article. No abstract available.

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