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Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass.
Chen AS, Marsh DJ, Trumbauer ME, Frazier EG, Guan XM, Yu H, Rosenblum CI, Vongs A, Feng Y, Cao L, Metzger JM, Strack AM, Camacho RE, Mellin TN, Nunes CN, Min W, Fisher J, Gopal-Truter S, MacIntyre DE, Chen HY, Van der Ploeg LH. Chen AS, et al. Among authors: frazier eg. Nat Genet. 2000 Sep;26(1):97-102. doi: 10.1038/79254. Nat Genet. 2000. PMID: 10973258
Role of the melanocortin-4 receptor in metabolic rate and food intake in mice.
Chen AS, Metzger JM, Trumbauer ME, Guan XM, Yu H, Frazier EG, Marsh DJ, Forrest MJ, Gopal-Truter S, Fisher J, Camacho RE, Strack AM, Mellin TN, MacIntyre DE, Chen HY, Van der Ploeg LH. Chen AS, et al. Among authors: frazier eg. Transgenic Res. 2000 Apr;9(2):145-54. doi: 10.1023/a:1008983615045. Transgenic Res. 2000. PMID: 10951699
Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism.
Marsh DJ, Weingarth DT, Novi DE, Chen HY, Trumbauer ME, Chen AS, Guan XM, Jiang MM, Feng Y, Camacho RE, Shen Z, Frazier EG, Yu H, Metzger JM, Kuca SJ, Shearman LP, Gopal-Truter S, MacNeil DJ, Strack AM, MacIntyre DE, Van der Ploeg LH, Qian S. Marsh DJ, et al. Among authors: frazier eg. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3240-5. doi: 10.1073/pnas.052706899. Epub 2002 Feb 26. Proc Natl Acad Sci U S A. 2002. PMID: 11867747 Free PMC article.
280 results