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The BRC repeats are conserved in mammalian BRCA2 proteins.
Bignell G, Micklem G, Stratton MR, Ashworth A, Wooster R. Bignell G, et al. Among authors: ashworth a. Hum Mol Genet. 1997 Jan;6(1):53-8. doi: 10.1093/hmg/6.1.53. Hum Mol Genet. 1997. PMID: 9002670
BRCA2 mutations in primary breast and ovarian cancers.
Lancaster JM, Wooster R, Mangion J, Phelan CM, Cochran C, Gumbs C, Seal S, Barfoot R, Collins N, Bignell G, Patel S, Hamoudi R, Larsson C, Wiseman RW, Berchuck A, Iglehart JD, Marks JR, Ashworth A, Stratton MR, Futreal PA. Lancaster JM, et al. Among authors: ashworth a. Nat Genet. 1996 Jun;13(2):238-40. doi: 10.1038/ng0696-238. Nat Genet. 1996. PMID: 8640235
A missense mutation in the BRCA2 gene in three siblings with ovarian cancer.
Roth S, Kristo P, Auranen A, Shayehgi M, Seal S, Collins N, Barfoot R, Rahman N, Klemi PJ, Grénman S, Sarantaus L, Nevanlinna H, Butzow R, Ashworth A, Stratton MR, Aaltonen LA. Roth S, et al. Among authors: ashworth a. Br J Cancer. 1998 Apr;77(8):1199-202. doi: 10.1038/bjc.1998.202. Br J Cancer. 1998. PMID: 9579822 Free PMC article.
Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer.
Ruark E, Snape K, Humburg P, Loveday C, Bajrami I, Brough R, Rodrigues DN, Renwick A, Seal S, Ramsay E, Duarte Sdel V, Rivas MA, Warren-Perry M, Zachariou A, Campion-Flora A, Hanks S, Murray A, Ansari Pour N, Douglas J, Gregory L, Rimmer A, Walker NM, Yang TP, Adlard JW, Barwell J, Berg J, Brady AF, Brewer C, Brice G, Chapman C, Cook J, Davidson R, Donaldson A, Douglas F, Eccles D, Evans DG, Greenhalgh L, Henderson A, Izatt L, Kumar A, Lalloo F, Miedzybrodzka Z, Morrison PJ, Paterson J, Porteous M, Rogers MT, Shanley S, Walker L, Gore M, Houlston R, Brown MA, Caufield MJ, Deloukas P, McCarthy MI, Todd JA; Breast and Ovarian Cancer Susceptibility Collaboration; Wellcome Trust Case Control Consortium; Turnbull C, Reis-Filho JS, Ashworth A, Antoniou AC, Lord CJ, Donnelly P, Rahman N. Ruark E, et al. Among authors: ashworth a. Nature. 2013 Jan 17;493(7432):406-10. doi: 10.1038/nature11725. Epub 2012 Dec 16. Nature. 2013. PMID: 23242139 Free PMC article.
Functions of the BRCA1 and BRCA2 genes.
Bertwistle D, Ashworth A. Bertwistle D, et al. Among authors: ashworth a. Curr Opin Genet Dev. 1998 Feb;8(1):14-20. doi: 10.1016/s0959-437x(98)80056-7. Curr Opin Genet Dev. 1998. PMID: 9529600 Review.
Phenotypic effects of heterozygosity for a BRCA2 mutation.
Warren M, Lord CJ, Masabanda J, Griffin D, Ashworth A. Warren M, et al. Among authors: ashworth a. Hum Mol Genet. 2003 Oct 15;12(20):2645-56. doi: 10.1093/hmg/ddg277. Epub 2003 Aug 19. Hum Mol Genet. 2003. PMID: 12928478
825 results