Ellsworth KP - Search Results

1

Effects of finasteride, a type 2 5-alpha reductase inhibitor, on fetal development in the rhesus monkey (Macaca mulatta).

Prahalada S, Tarantal AF, Harris GS, Ellsworth KP, Clarke AP, Skiles GL, MacKenzie KI, Kruk LF, Ablin DS, Cukierski MA, Peter CP, vanZwieten MJ, Hendrickx AG. Prahalada S, et al. Among authors: ellsworth kp. Teratology. 1997 Feb;55(2):119-31. doi: 10.1002/(SICI)1096-9926(199702)55:2<119::AID-TERA1>3.0.CO;2-Z. Teratology. 1997. PMID: 9143092

2

Expression of the type 1 and 2 steroid 5 alpha-reductases in human fetal tissues.

Ellsworth K, Harris G. Ellsworth K, et al. Biochem Biophys Res Commun. 1995 Oct 13;215(2):774-80. doi: 10.1006/bbrc.1995.2530. Biochem Biophys Res Commun. 1995. PMID: 7488021

3

Cloning, expression and characterization of rhesus macaque types 1 and 2 5alpha-reductase: evidence for mechanism-based inhibition by finasteride.

Ellsworth KP, Azzolina BA, Cimis G, Bull HG, Harris GS. Ellsworth KP, et al. J Steroid Biochem Mol Biol. 1998 Sep;66(5-6):271-9. doi: 10.1016/s0960-0760(98)00059-4. J Steroid Biochem Mol Biol. 1998. PMID: 9749833

4

Inhibition of rat alpha-reductases by finasteride: evidence for isozyme differences in the mechanism of inhibition.

Azzolina B, Ellsworth K, Andersson S, Geissler W, Bull HG, Harris GS. Azzolina B, et al. J Steroid Biochem Mol Biol. 1997 Apr;61(1-2):55-64. doi: 10.1016/s0960-0760(97)00002-2. J Steroid Biochem Mol Biol. 1997. PMID: 9328210

5

Identification and selective inhibition of an isozyme of steroid 5 alpha-reductase in human scalp.

Harris G, Azzolina B, Baginsky W, Cimis G, Rasmusson GH, Tolman RL, Raetz CR, Ellsworth K. Harris G, et al. Proc Natl Acad Sci U S A. 1992 Nov 15;89(22):10787-91. doi: 10.1073/pnas.89.22.10787. Proc Natl Acad Sci U S A. 1992. PMID: 1438277 Free PMC article.

6

MK386: a potent, selective inhibitor of the human type 1 5alpha-reductase.

Ellsworth K, Azzolina B, Baginsky W, Bull H, Chang B, Cimis G, Mitra S, Toney J, Bakshi RK, Rasmusson GR, Tolman RL, Harris GS. Ellsworth K, et al. J Steroid Biochem Mol Biol. 1996 Jul;58(4):377-84. doi: 10.1016/0960-0760(96)00050-7. J Steroid Biochem Mol Biol. 1996. PMID: 8903421

7

4,7 beta-Dimethyl-4-azacholestan-3-one (MK-386) and related 4-azasteroids as selective inhibitors of human type 1 5 alpha-reductase.

Bakshi RK, Patel GF, Rasmusson GH, Baginsky WF, Cimis G, Ellsworth K, Chang B, Bull H, Tolman RL, Harris GS. Bakshi RK, et al. J Med Chem. 1994 Nov 11;37(23):3871-4. doi: 10.1021/jm00049a003. J Med Chem. 1994. PMID: 7966146 No abstract available.

8

4-Aza-3-oxo-5 alpha-androst-1-ene-17 beta-N-aryl-carboxamides as dual inhibitors of human type 1 and type 2 steroid 5 alpha-reductases. Dramatic effect of N-aryl substituents on type 1 and type 2 5 alpha-reductase inhibitory potency.

Bakshi RK, Rasmusson GH, Patel GF, Mosley RT, Chang B, Ellsworth K, Harris GS, Tolman RL. Bakshi RK, et al. J Med Chem. 1995 Aug 18;38(17):3189-92. doi: 10.1021/jm00017a001. J Med Chem. 1995. PMID: 7650670 No abstract available.

9

Design and synthesis of novel antibacterial agents with inhibitory activity against DNA polymerase III.

Ali A, Aster SD, Graham DW, Patel GF, Taylor GE, Tolman RL, Painter RE, Silver LL, Young K, Ellsworth K, Geissler W, Harris GS. Ali A, et al. Bioorg Med Chem Lett. 2001 Aug 20;11(16):2185-8. doi: 10.1016/s0960-894x(01)00407-3. Bioorg Med Chem Lett. 2001. PMID: 11514166

10

Novel pyrazolo[3,4-d]pyrimidine-based inhibitors of Staphlococcus aureus DNA polymerase III: design, synthesis, and biological evaluation.

Ali A, Taylor GE, Ellsworth K, Harris G, Painter R, Silver LL, Young K. Ali A, et al. J Med Chem. 2003 May 8;46(10):1824-30. doi: 10.1021/jm020483c. J Med Chem. 2003. PMID: 12723946

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