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Functional interactions between the proline-rich and repeat regions of tau enhance microtubule binding and assembly.
Mol Biol Cell. 1997 Feb;8(2):353-65. doi: 10.1091/mbc.8.2.353.
Mol Biol Cell. 1997.
PMID: 9190213
Free PMC article.
Structural and functional differences between 3-repeat and 4-repeat tau isoforms. Implications for normal tau function and the onset of neurodegenetative disease.
Goode BL, Chau M, Denis PE, Feinstein SC.
Goode BL, et al. Among authors: denis pe.
J Biol Chem. 2000 Dec 8;275(49):38182-9. doi: 10.1074/jbc.M007489200.
J Biol Chem. 2000.
PMID: 10984497
Free article.
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Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation.
Narhi L, Wood SJ, Steavenson S, Jiang Y, Wu GM, Anafi D, Kaufman SA, Martin F, Sitney K, Denis P, Louis JC, Wypych J, Biere AL, Citron M.
Narhi L, et al.
J Biol Chem. 1999 Apr 2;274(14):9843-6. doi: 10.1074/jbc.274.14.9843.
J Biol Chem. 1999.
PMID: 10092675
Free article.
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Characterization of Alzheimer's beta -secretase protein BACE. A pepsin family member with unusual properties.
Haniu M, Denis P, Young Y, Mendiaz EA, Fuller J, Hui JO, Bennett BD, Kahn S, Ross S, Burgess T, Katta V, Rogers G, Vassar R, Citron M.
Haniu M, et al.
J Biol Chem. 2000 Jul 14;275(28):21099-106. doi: 10.1074/jbc.M002095200.
J Biol Chem. 2000.
PMID: 10887202
Free article.
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Polyglutamine repeat length-dependent proteolysis of huntingtin.
Sun B, Fan W, Balciunas A, Cooper JK, Bitan G, Steavenson S, Denis PE, Young Y, Adler B, Daugherty L, Manoukian R, Elliott G, Shen W, Talvenheimo J, Teplow DB, Haniu M, Haldankar R, Wypych J, Ross CA, Citron M, Richards WG.
Sun B, et al. Among authors: denis pe.
Neurobiol Dis. 2002 Oct;11(1):111-22. doi: 10.1006/nbdi.2002.0539.
Neurobiol Dis. 2002.
PMID: 12460551
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A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta -secretase.
Bennett BD, Denis P, Haniu M, Teplow DB, Kahn S, Louis JC, Citron M, Vassar R.
Bennett BD, et al.
J Biol Chem. 2000 Dec 1;275(48):37712-7. doi: 10.1074/jbc.M005339200.
J Biol Chem. 2000.
PMID: 10956649
Free article.
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Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation.
Luo Y, Bolon B, Kahn S, Bennett BD, Babu-Khan S, Denis P, Fan W, Kha H, Zhang J, Gong Y, Martin L, Louis JC, Yan Q, Richards WG, Citron M, Vassar R.
Luo Y, et al.
Nat Neurosci. 2001 Mar;4(3):231-2. doi: 10.1038/85059.
Nat Neurosci. 2001.
PMID: 11224535
No abstract available.
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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
Vassar R, Bennett BD, Babu-Khan S, Kahn S, Mendiaz EA, Denis P, Teplow DB, Ross S, Amarante P, Loeloff R, Luo Y, Fisher S, Fuller J, Edenson S, Lile J, Jarosinski MA, Biere AL, Curran E, Burgess T, Louis JC, Collins F, Treanor J, Rogers G, Citron M.
Vassar R, et al.
Science. 1999 Oct 22;286(5440):735-41. doi: 10.1126/science.286.5440.735.
Science. 1999.
PMID: 10531052
Free article.
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