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Lack of evidence from HPLC 32P-post-labelling for tamoxifen-DNA adducts in the human endometrium.
Carmichael PL, Sardar S, Crooks N, Neven P, Van Hoof I, Ugwumadu A, Bourne T, Tomas E, Hellberg P, Hewer AJ, Phillips DH. Carmichael PL, et al. Among authors: hewer aj. Carcinogenesis. 1999 Feb;20(2):339-42. doi: 10.1093/carcin/20.2.339. Carcinogenesis. 1999. PMID: 10069474
Tamoxifen is associated with an increased incidence of endometrial cancer in women. It is also a potent carcinogen in rat liver and forms covalent DNA adducts in this tissue. A previous study exploring DNA adducts in human endometria, utilizing thin layer chromatogr …
Tamoxifen is associated with an increased incidence of endometrial cancer in women. It is also a potent carcinogen in rat liver and f …
157 results