Krasowski MD - Search Results

1

A deficit of functional GABA(A) receptors in neurons of beta 3 subunit knockout mice.

Krasowski MD, Rick CE, Harrison NL, Firestone LL, Homanics GE. Krasowski MD, et al. Neurosci Lett. 1998 Jan 9;240(2):81-4. doi: 10.1016/s0304-3940(97)00929-4. Neurosci Lett. 1998. PMID: 9486477 Free PMC article.

2

Alpha subunit isoform influences GABA(A) receptor modulation by propofol.

Krasowski MD, O'Shea SM, Rick CE, Whiting PJ, Hadingham KL, Czajkowski C, Harrison NL. Krasowski MD, et al. Neuropharmacology. 1997 Jul;36(7):941-9. doi: 10.1016/s0028-3908(97)00074-9. Neuropharmacology. 1997. PMID: 9257938 Free PMC article.

3

Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy, cleft palate, and hypersensitive behavior.

Homanics GE, DeLorey TM, Firestone LL, Quinlan JJ, Handforth A, Harrison NL, Krasowski MD, Rick CE, Korpi ER, Mäkelä R, Brilliant MH, Hagiwara N, Ferguson C, Snyder K, Olsen RW. Homanics GE, et al. Among authors: krasowski md. Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):4143-8. doi: 10.1073/pnas.94.8.4143. Proc Natl Acad Sci U S A. 1997. PMID: 9108119 Free PMC article.

4

Propofol and other intravenous anesthetics have sites of action on the gamma-aminobutyric acid type A receptor distinct from that for isoflurane.

Krasowski MD, Koltchine VV, Rick CE, Ye Q, Finn SE, Harrison NL. Krasowski MD, et al. Mol Pharmacol. 1998 Mar;53(3):530-8. doi: 10.1124/mol.53.3.530. Mol Pharmacol. 1998. PMID: 9495821

5

Trichloroethanol modulation of recombinant GABAA, glycine and GABA rho 1 receptors.

Krasowski MD, Finn SE, Ye Q, Harrison NL. Krasowski MD, et al. J Pharmacol Exp Ther. 1998 Mar;284(3):934-42. J Pharmacol Exp Ther. 1998. PMID: 9495852

6

Normal electrophysiological and behavioral responses to ethanol in mice lacking the long splice variant of the gamma2 subunit of the gamma-aminobutyrate type A receptor.

Homanics GE, Harrison NL, Quinlan JJ, Krasowski MD, Rick CE, de Blas AL, Mehta AK, Kist F, Mihalek RM, Aul JJ, Firestone LL. Homanics GE, et al. Among authors: krasowski md. Neuropharmacology. 1999 Feb;38(2):253-65. doi: 10.1016/s0028-3908(98)00177-4. Neuropharmacology. 1999. PMID: 10218866 Free PMC article.

7

General anaesthetic actions on ligand-gated ion channels.

Krasowski MD, Harrison NL. Krasowski MD, et al. Cell Mol Life Sci. 1999 Aug 15;55(10):1278-303. doi: 10.1007/s000180050371. Cell Mol Life Sci. 1999. PMID: 10487207 Free PMC article. Review.

8

The actions of ether, alcohol and alkane general anaesthetics on GABAA and glycine receptors and the effects of TM2 and TM3 mutations.

Krasowski MD, Harrison NL. Krasowski MD, et al. Br J Pharmacol. 2000 Feb;129(4):731-43. doi: 10.1038/sj.bjp.0703087. Br J Pharmacol. 2000. PMID: 10683198 Free PMC article.

9

Methionine 286 in transmembrane domain 3 of the GABAA receptor beta subunit controls a binding cavity for propofol and other alkylphenol general anesthetics.

Krasowski MD, Nishikawa K, Nikolaeva N, Lin A, Harrison NL. Krasowski MD, et al. Neuropharmacology. 2001 Dec;41(8):952-64. doi: 10.1016/s0028-3908(01)00141-1. Neuropharmacology. 2001. PMID: 11747900 Free PMC article.

10

4D-QSAR analysis of a set of propofol analogues: mapping binding sites for an anesthetic phenol on the GABA(A) receptor.

Krasowski MD, Hong X, Hopfinger AJ, Harrison NL. Krasowski MD, et al. J Med Chem. 2002 Jul 18;45(15):3210-21. doi: 10.1021/jm010461a. J Med Chem. 2002. PMID: 12109905 Free PMC article.

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