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Linkage of familial combined hyperlipidaemia to chromosome 1q21-q23.
Pajukanta P, Nuotio I, Terwilliger JD, Porkka KV, Ylitalo K, Pihlajamäki J, Suomalainen AJ, Syvänen AC, Lehtimäki T, Viikari JS, Laakso M, Taskinen MR, Ehnholm C, Peltonen L. Pajukanta P, et al. Among authors: laakso m. Nat Genet. 1998 Apr;18(4):369-73. doi: 10.1038/ng0498-369. Nat Genet. 1998. PMID: 9537421
Genomewide scan for familial combined hyperlipidemia genes in finnish families, suggesting multiple susceptibility loci influencing triglyceride, cholesterol, and apolipoprotein B levels.
Pajukanta P, Terwilliger JD, Perola M, Hiekkalinna T, Nuotio I, Ellonen P, Parkkonen M, Hartiala J, Ylitalo K, Pihlajamäki J, Porkka K, Laakso M, Viikari J, Ehnholm C, Taskinen MR, Peltonen L. Pajukanta P, et al. Among authors: laakso m. Am J Hum Genet. 1999 May;64(5):1453-63. doi: 10.1086/302365. Am J Hum Genet. 1999. PMID: 10205279 Free PMC article.
Two loci on chromosomes 2 and X for premature coronary heart disease identified in early- and late-settlement populations of Finland.
Pajukanta P, Cargill M, Viitanen L, Nuotio I, Kareinen A, Perola M, Terwilliger JD, Kempas E, Daly M, Lilja H, Rioux JD, Brettin T, Viikari JS, Rönnemaa T, Laakso M, Lander ES, Peltonen L. Pajukanta P, et al. Among authors: laakso m. Am J Hum Genet. 2000 Dec;67(6):1481-93. doi: 10.1086/316902. Epub 2000 Nov 13. Am J Hum Genet. 2000. PMID: 11078477 Free PMC article.
G-250A substitution in promoter of hepatic lipase gene is associated with dyslipidemia and insulin resistance in healthy control subjects and in members of families with familial combined hyperlipidemia.
Pihlajamäki J, Karjalainen L, Karhapää P, Vauhkonen I, Taskinen MR, Deeb SS, Laakso M. Pihlajamäki J, et al. Among authors: laakso m. Arterioscler Thromb Vasc Biol. 2000 Jul;20(7):1789-95. doi: 10.1161/01.atv.20.7.1789. Arterioscler Thromb Vasc Biol. 2000. PMID: 10894818
New genetic loci link adipose and insulin biology to body fat distribution.
Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JMW, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C, Gustafsson S, Day FR, Esko T, Fall T, Kutalik Z, Luan J, Randall JC, Scherag A, Vedantam S, Wood AR, Chen J, Fehrmann R, Karjalainen J, Kahali B, Liu CT, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bragg-Gresham JL, Buyske S, Demirkan A, Ehret GB, Feitosa MF, Goel A, Jackson AU, Johnson T, Kleber ME, Kristiansson K, Mangino M, Leach IM, Medina-Gomez C, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Stančáková A, Sung YJ, Tanaka T, Teumer A, Van Vliet-Ostaptchouk JV, Yengo L, Zhang W, Albrecht E, Ärnlöv J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Blüher M, Böhringer S, Bonnet F, Böttcher Y, Bruinenberg M, Carba DB, Caspersen IH, Clarke R, Daw EW, Deelen J, Deelman E, Delgado G, Doney AS, Eklund N, Erdos MR, Estrada K, Eury E, Friedrich N, Garcia ME, Giedraitis V, Gigante B, Go AS, Golay A, Grallert H, Grammer TB, Gräßler J, Grewal J, Groves CJ, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heikkilä K, Herzig KH, Helmer Q, Hi… See abstract for full author list ➔ Shungin D, et al. Among authors: laakso m. Nature. 2015 Feb 12;518(7538):187-196. doi: 10.1038/nature14132. Nature. 2015. PMID: 25673412 Free PMC article.
Different regulation of free fatty acid levels and glucose oxidation by the Trp64Arg polymorphism of the beta3-adrenergic receptor gene and the promoter variant (A-3826G) of the uncoupling protein 1 gene in familial combined hyperlipidemia.
Pihlajamäki J, Rissanen J, Valve R, Heikkinen S, Karjalainen L, Laakso M. Pihlajamäki J, et al. Among authors: laakso m. Metabolism. 1998 Nov;47(11):1397-402. doi: 10.1016/s0026-0495(98)90312-2. Metabolism. 1998. PMID: 9826220
1,375 results