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The Asn9 variant of lipoprotein lipase is associated with the -93G promoter mutation and an increased risk of coronary artery disease. The Regress Study Group.
Kastelein JJ, Groenemeyer BE, Hallman DM, Henderson H, Reymer PW, Gagné SE, Jansen H, Seidell JC, Kromhout D, Jukema JW, Bruschke AV, Boerwinkle E, Hayden MR. Kastelein JJ, et al. Among authors: reymer pw. Clin Genet. 1998 Jan;53(1):27-33. doi: 10.1034/j.1399-0004.1998.531530106.x. Clin Genet. 1998. PMID: 9550358
Patients with apoE3 deficiency (E2/2, E3/2, and E4/2) who manifest with hyperlipidemia have increased frequency of an Asn 291-->Ser mutation in the human LPL gene.
Zhang H, Reymer PW, Liu MS, Forsythe IJ, Groenemeyer BE, Frohlich J, Brunzell JD, Kastelein JJ, Hayden MR, Ma Y. Zhang H, et al. Among authors: reymer pw. Arterioscler Thromb Vasc Biol. 1995 Oct;15(10):1695-703. doi: 10.1161/01.atv.15.10.1695. Arterioscler Thromb Vasc Biol. 1995. PMID: 7583546
Genetic variant showing a positive interaction with beta-blocking agents with a beneficial influence on lipoprotein lipase activity, HDL cholesterol, and triglyceride levels in coronary artery disease patients. The Ser447-stop substitution in the lipoprotein lipase gene. REGRESS Study Group.
Groenemeijer BE, Hallman MD, Reymer PW, Gagné E, Kuivenhoven JA, Bruin T, Jansen H, Lie KI, Bruschke AV, Boerwinkle E, Hayden MR, Kastelein JJ. Groenemeijer BE, et al. Among authors: reymer pw. Circulation. 1997 Jun 17;95(12):2628-35. doi: 10.1161/01.cir.95.12.2628. Circulation. 1997. PMID: 9193431 Clinical Trial.
Apolipoprotein E genotyping on agarose gels.
Reymer PW, Groenemeyer BE, van de Burg R, Kastelein JJ. Reymer PW, et al. Clin Chem. 1995 Jul;41(7):1046-7. Clin Chem. 1995. PMID: 7600689 No abstract available.
18 results