Clarke LL - Search Results

1

Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger.

Schultheis PJ, Clarke LL, Meneton P, Miller ML, Soleimani M, Gawenis LR, Riddle TM, Duffy JJ, Doetschman T, Wang T, Giebisch G, Aronson PS, Lorenz JN, Shull GE. Schultheis PJ, et al. Among authors: clarke ll. Nat Genet. 1998 Jul;19(3):282-5. doi: 10.1038/969. Nat Genet. 1998. PMID: 9662405

2

Colonic anion secretory defects and metabolic acidosis in mice lacking the NBC1 Na+/HCO3- cotransporter.

Gawenis LR, Bradford EM, Prasad V, Lorenz JN, Simpson JE, Clarke LL, Woo AL, Grisham C, Sanford LP, Doetschman T, Miller ML, Shull GE. Gawenis LR, et al. Among authors: clarke ll. J Biol Chem. 2007 Mar 23;282(12):9042-52. doi: 10.1074/jbc.M607041200. Epub 2006 Dec 27. J Biol Chem. 2007. PMID: 17192275 Free article.

3

Reduced NHE3-mediated Na+ absorption increases survival and decreases the incidence of intestinal obstructions in cystic fibrosis mice.

Bradford EM, Sartor MA, Gawenis LR, Clarke LL, Shull GE. Bradford EM, et al. Among authors: clarke ll. Am J Physiol Gastrointest Liver Physiol. 2009 Apr;296(4):G886-98. doi: 10.1152/ajpgi.90520.2008. Epub 2009 Jan 22. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19164484 Free PMC article.

4

Colonic H(+)-K(+)-ATPase in K(+) conservation and electrogenic Na(+) absorption during Na(+) restriction.

Spicer Z, Clarke LL, Gawenis LR, Shull GE. Spicer Z, et al. Among authors: clarke ll. Am J Physiol Gastrointest Liver Physiol. 2001 Dec;281(6):G1369-77. doi: 10.1152/ajpgi.2001.281.6.G1369. Am J Physiol Gastrointest Liver Physiol. 2001. PMID: 11705741 Free article.

5

Targeted disruption of the murine Na+/H+ exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion.

Schultheis PJ, Clarke LL, Meneton P, Harline M, Boivin GP, Stemmermann G, Duffy JJ, Doetschman T, Miller ML, Shull GE. Schultheis PJ, et al. Among authors: clarke ll. J Clin Invest. 1998 Mar 15;101(6):1243-53. doi: 10.1172/JCI1249. J Clin Invest. 1998. PMID: 9502765 Free PMC article.

6

Mice lacking the basolateral Na-K-2Cl cotransporter have impaired epithelial chloride secretion and are profoundly deaf.

Flagella M, Clarke LL, Miller ML, Erway LC, Giannella RA, Andringa A, Gawenis LR, Kramer J, Duffy JJ, Doetschman T, Lorenz JN, Yamoah EN, Cardell EL, Shull GE. Flagella M, et al. Among authors: clarke ll. J Biol Chem. 1999 Sep 17;274(38):26946-55. doi: 10.1074/jbc.274.38.26946. J Biol Chem. 1999. PMID: 10480906 Free article.

7

Increased sensitivity to K+ deprivation in colonic H,K-ATPase-deficient mice.

Meneton P, Schultheis PJ, Greeb J, Nieman ML, Liu LH, Clarke LL, Duffy JJ, Doetschman T, Lorenz JN, Shull GE. Meneton P, et al. Among authors: clarke ll. J Clin Invest. 1998 Feb 1;101(3):536-42. doi: 10.1172/JCI1720. J Clin Invest. 1998. PMID: 9449685 Free PMC article.

8

Intestinal NaCl transport in NHE2 and NHE3 knockout mice.

Gawenis LR, Stien X, Shull GE, Schultheis PJ, Woo AL, Walker NM, Clarke LL. Gawenis LR, et al. Among authors: clarke ll. Am J Physiol Gastrointest Liver Physiol. 2002 May;282(5):G776-84. doi: 10.1152/ajpgi.00297.2001. Am J Physiol Gastrointest Liver Physiol. 2002. PMID: 11960774 Free article.

9

Uroguanylin knockout mice have increased blood pressure and impaired natriuretic response to enteral NaCl load.

Lorenz JN, Nieman M, Sabo J, Sanford LP, Hawkins JA, Elitsur N, Gawenis LR, Clarke LL, Cohen MB. Lorenz JN, et al. Among authors: clarke ll. J Clin Invest. 2003 Oct;112(8):1244-54. doi: 10.1172/JCI18743. J Clin Invest. 2003. PMID: 14561709 Free PMC article.

10

PAT-1 (Slc26a6) is the predominant apical membrane Cl-/HCO3- exchanger in the upper villous epithelium of the murine duodenum.

Simpson JE, Schweinfest CW, Shull GE, Gawenis LR, Walker NM, Boyle KT, Soleimani M, Clarke LL. Simpson JE, et al. Among authors: clarke ll. Am J Physiol Gastrointest Liver Physiol. 2007 Apr;292(4):G1079-88. doi: 10.1152/ajpgi.00354.2006. Epub 2006 Dec 14. Am J Physiol Gastrointest Liver Physiol. 2007. PMID: 17170027 Free article.

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