Doetschman T - Search Results

1

Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger.

Schultheis PJ, Clarke LL, Meneton P, Miller ML, Soleimani M, Gawenis LR, Riddle TM, Duffy JJ, Doetschman T, Wang T, Giebisch G, Aronson PS, Lorenz JN, Shull GE. Schultheis PJ, et al. Among authors: doetschman t. Nat Genet. 1998 Jul;19(3):282-5. doi: 10.1038/969. Nat Genet. 1998. PMID: 9662405

2

Impaired renal NaCl absorption in mice lacking the ROMK potassium channel, a model for type II Bartter's syndrome.

Lorenz JN, Baird NR, Judd LM, Noonan WT, Andringa A, Doetschman T, Manning PA, Liu LH, Miller ML, Shull GE. Lorenz JN, et al. Among authors: doetschman t. J Biol Chem. 2002 Oct 4;277(40):37871-80. doi: 10.1074/jbc.M205627200. Epub 2002 Jul 16. J Biol Chem. 2002. PMID: 12122007 Free article.

3

Colonic anion secretory defects and metabolic acidosis in mice lacking the NBC1 Na+/HCO3- cotransporter.

Gawenis LR, Bradford EM, Prasad V, Lorenz JN, Simpson JE, Clarke LL, Woo AL, Grisham C, Sanford LP, Doetschman T, Miller ML, Shull GE. Gawenis LR, et al. Among authors: doetschman t. J Biol Chem. 2007 Mar 23;282(12):9042-52. doi: 10.1074/jbc.M607041200. Epub 2006 Dec 27. J Biol Chem. 2007. PMID: 17192275 Free article.

4

Increased sensitivity to K+ deprivation in colonic H,K-ATPase-deficient mice.

Meneton P, Schultheis PJ, Greeb J, Nieman ML, Liu LH, Clarke LL, Duffy JJ, Doetschman T, Lorenz JN, Shull GE. Meneton P, et al. Among authors: doetschman t. J Clin Invest. 1998 Feb 1;101(3):536-42. doi: 10.1172/JCI1720. J Clin Invest. 1998. PMID: 9449685 Free PMC article.

5

Targeted disruption of the murine Na+/H+ exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion.

Schultheis PJ, Clarke LL, Meneton P, Harline M, Boivin GP, Stemmermann G, Duffy JJ, Doetschman T, Miller ML, Shull GE. Schultheis PJ, et al. Among authors: doetschman t. J Clin Invest. 1998 Mar 15;101(6):1243-53. doi: 10.1172/JCI1249. J Clin Invest. 1998. PMID: 9502765 Free PMC article.

6

Phenotype resembling Gitelman's syndrome in mice lacking the apical Na+-Cl- cotransporter of the distal convoluted tubule.

Schultheis PJ, Lorenz JN, Meneton P, Nieman ML, Riddle TM, Flagella M, Duffy JJ, Doetschman T, Miller ML, Shull GE. Schultheis PJ, et al. Among authors: doetschman t. J Biol Chem. 1998 Oct 30;273(44):29150-5. doi: 10.1074/jbc.273.44.29150. J Biol Chem. 1998. PMID: 9786924 Free article.

7

Mice lacking the basolateral Na-K-2Cl cotransporter have impaired epithelial chloride secretion and are profoundly deaf.

Flagella M, Clarke LL, Miller ML, Erway LC, Giannella RA, Andringa A, Gawenis LR, Kramer J, Duffy JJ, Doetschman T, Lorenz JN, Yamoah EN, Cardell EL, Shull GE. Flagella M, et al. Among authors: doetschman t. J Biol Chem. 1999 Sep 17;274(38):26946-55. doi: 10.1074/jbc.274.38.26946. J Biol Chem. 1999. PMID: 10480906 Free article.

8

Stomachs of mice lacking the gastric H,K-ATPase alpha -subunit have achlorhydria, abnormal parietal cells, and ciliated metaplasia.

Spicer Z, Miller ML, Andringa A, Riddle TM, Duffy JJ, Doetschman T, Shull GE. Spicer Z, et al. Among authors: doetschman t. J Biol Chem. 2000 Jul 14;275(28):21555-65. doi: 10.1074/jbc.M001558200. J Biol Chem. 2000. PMID: 10764766 Free article.

9

Impaired cardiac contractility in mice lacking both the AE3 Cl-/HCO3- exchanger and the NKCC1 Na+-K+-2Cl- cotransporter: effects on Ca2+ handling and protein phosphatases.

Prasad V, Bodi I, Meyer JW, Wang Y, Ashraf M, Engle SJ, Doetschman T, Sisco K, Nieman ML, Miller ML, Lorenz JN, Shull GE. Prasad V, et al. Among authors: doetschman t. J Biol Chem. 2008 Nov 14;283(46):31303-14. doi: 10.1074/jbc.M803706200. Epub 2008 Sep 8. J Biol Chem. 2008. PMID: 18779325 Free PMC article.

10

Mice with a targeted disruption of the AE2 Cl-/HCO3- exchanger are achlorhydric.

Gawenis LR, Ledoussal C, Judd LM, Prasad V, Alper SL, Stuart-Tilley A, Woo AL, Grisham C, Sanford LP, Doetschman T, Miller ML, Shull GE. Gawenis LR, et al. Among authors: doetschman t. J Biol Chem. 2004 Jul 16;279(29):30531-9. doi: 10.1074/jbc.M403779200. Epub 2004 Apr 30. J Biol Chem. 2004. PMID: 15123620 Free article.

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