Goodchild J - Search Results

1

Intracellular metabolism of a 2'-O-methyl-stabilized ribozyme after uptake by DOTAP transfection or asfree ribozyme. A study by capillary electrophoresis.

Prasmickaite L, Hogset A, Maelandsmo G, Berg K, Goodchild J, Perkins T, Fodstad O, Hovig E. Prasmickaite L, et al. Among authors: goodchild j. Nucleic Acids Res. 1998 Sep 15;26(18):4241-8. doi: 10.1093/nar/26.18.4241. Nucleic Acids Res. 1998. PMID: 9722645 Free PMC article.

2

Optimization of hammerhead ribozymes for the cleavage of S100A4 (CAPL) mRNA.

Hovig E, Maelandsmo G, Mellingsaeter T, Fodstad O, Mielewczyk SS, Wolfe J, Goodchild J. Hovig E, et al. Among authors: goodchild j. Antisense Nucleic Acid Drug Dev. 2001 Apr;11(2):67-75. doi: 10.1089/108729001750171272. Antisense Nucleic Acid Drug Dev. 2001. PMID: 11334142

3

Fluorescence resonance energy transfer analysis of ribozyme kinetics reveals the mode of action of a facilitator oligonucleotide.

Perkins TA, Wolf DE, Goodchild J. Perkins TA, et al. Among authors: goodchild j. Biochemistry. 1996 Dec 17;35(50):16370-7. doi: 10.1021/bi961234r. Biochemistry. 1996. PMID: 8973213

4

Using fluorescence resonance energy transfer to investigate hammerhead ribozyme kinetics.

Perkins TA, Goodchild J. Perkins TA, et al. Among authors: goodchild j. Methods Mol Biol. 1997;74:241-51. doi: 10.1385/0-89603-389-9:241. Methods Mol Biol. 1997. PMID: 9204439 No abstract available.

5

Enhancement of ribozyme catalytic activity by a contiguous oligodeoxynucleotide (facilitator) and by 2'-O-methylation.

Goodchild J. Goodchild J. Nucleic Acids Res. 1992 Sep 11;20(17):4607-12. doi: 10.1093/nar/20.17.4607. Nucleic Acids Res. 1992. PMID: 1383929 Free PMC article.

6

A novel assay for DNA ligase.

Goodchild J, Vishwanatha JK. Goodchild J, et al. Nucleic Acids Res. 1991 Jul 11;19(13):3745. doi: 10.1093/nar/19.13.3745. Nucleic Acids Res. 1991. PMID: 1852614 Free PMC article.

7

DNA ligase I is associated with the 21 S complex of enzymes for DNA synthesis in HeLa cells.

Li C, Goodchild J, Baril EF. Li C, et al. Among authors: goodchild j. Nucleic Acids Res. 1994 Feb 25;22(4):632-8. doi: 10.1093/nar/22.4.632. Nucleic Acids Res. 1994. PMID: 8127711 Free PMC article.

8

Antisense antivirals.

Goodchild J. Goodchild J. Antisense Res Dev. 1991 Winter;1(4):361-4. doi: 10.1089/ard.1991.1.361. Antisense Res Dev. 1991. PMID: 1821657 Review.

9

In vitro optimization of truncated stem-loop II variants of the hammerhead ribozyme for cleavage in low concentrations of magnesium under non-turnover conditions.

Zillmann M, Limauro SE, Goodchild J. Zillmann M, et al. Among authors: goodchild j. RNA. 1997 Jul;3(7):734-47. RNA. 1997. PMID: 9214657 Free PMC article.

10

Ribozymes that cleave an RNA sequence from human immunodeficiency virus: the effect of flanking sequence on rate.

Goodchild J, Kohli V. Goodchild J, et al. Arch Biochem Biophys. 1991 Feb 1;284(2):386-91. doi: 10.1016/0003-9861(91)90313-8. Arch Biochem Biophys. 1991. PMID: 1989522

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