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Synthesis and biological activities of potent peptidomimetics selective for somatostatin receptor subtype 2.
Yang L, Berk SC, Rohrer SP, Mosley RT, Guo L, Underwood DJ, Arison BH, Birzin ET, Hayes EC, Mitra SW, Parmar RM, Cheng K, Wu TJ, Butler BS, Foor F, Pasternak A, Pan Y, Silva M, Freidinger RM, Smith RG, Chapman K, Schaeffer JM, Patchett AA. Yang L, et al. Among authors: mitra sw. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10836-41. doi: 10.1073/pnas.95.18.10836. Proc Natl Acad Sci U S A. 1998. PMID: 9724791 Free PMC article.
Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry.
Rohrer SP, Birzin ET, Mosley RT, Berk SC, Hutchins SM, Shen DM, Xiong Y, Hayes EC, Parmar RM, Foor F, Mitra SW, Degrado SJ, Shu M, Klopp JM, Cai SJ, Blake A, Chan WW, Pasternak A, Yang L, Patchett AA, Smith RG, Chapman KT, Schaeffer JM. Rohrer SP, et al. Among authors: mitra sw. Science. 1998 Oct 23;282(5389):737-40. doi: 10.1126/science.282.5389.737. Science. 1998. PMID: 9784130
The discovery of tetrahydrofluorenones as a new class of estrogen receptor beta-subtype selective ligands.
Wilkening RR, Ratcliffe RW, Tynebor EC, Wildonger KJ, Fried AK, Hammond ML, Mosley RT, Fitzgerald PM, Sharma N, McKeever BM, Nilsson S, Carlquist M, Thorsell A, Locco L, Katz R, Frisch K, Birzin ET, Wilkinson HA, Mitra S, Cai S, Hayes EC, Schaeffer JM, Rohrer SP. Wilkening RR, et al. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3489-94. doi: 10.1016/j.bmcl.2006.03.098. Epub 2006 May 2. Bioorg Med Chem Lett. 2006. PMID: 16632357
MK386: a potent, selective inhibitor of the human type 1 5alpha-reductase.
Ellsworth K, Azzolina B, Baginsky W, Bull H, Chang B, Cimis G, Mitra S, Toney J, Bakshi RK, Rasmusson GR, Tolman RL, Harris GS. Ellsworth K, et al. J Steroid Biochem Mol Biol. 1996 Jul;58(4):377-84. doi: 10.1016/0960-0760(96)00050-7. J Steroid Biochem Mol Biol. 1996. PMID: 8903421
16 results