Mosley RT - Search Results

1

Synthesis and biological activities of potent peptidomimetics selective for somatostatin receptor subtype 2.

Yang L, Berk SC, Rohrer SP, Mosley RT, Guo L, Underwood DJ, Arison BH, Birzin ET, Hayes EC, Mitra SW, Parmar RM, Cheng K, Wu TJ, Butler BS, Foor F, Pasternak A, Pan Y, Silva M, Freidinger RM, Smith RG, Chapman K, Schaeffer JM, Patchett AA. Yang L, et al. Among authors: mosley rt. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10836-41. doi: 10.1073/pnas.95.18.10836. Proc Natl Acad Sci U S A. 1998. PMID: 9724791 Free PMC article.

2

Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry.

Rohrer SP, Birzin ET, Mosley RT, Berk SC, Hutchins SM, Shen DM, Xiong Y, Hayes EC, Parmar RM, Foor F, Mitra SW, Degrado SJ, Shu M, Klopp JM, Cai SJ, Blake A, Chan WW, Pasternak A, Yang L, Patchett AA, Smith RG, Chapman KT, Schaeffer JM. Rohrer SP, et al. Among authors: mosley rt. Science. 1998 Oct 23;282(5389):737-40. doi: 10.1126/science.282.5389.737. Science. 1998. PMID: 9784130

3

A combinatorial approach toward the discovery of non-peptide, subtype-selective somatostatin receptor ligands.

Berk SC, Rohrer SP, Degrado SJ, Birzin ET, Mosley RT, Hutchins SM, Pasternak A, Schaeffer JM, Underwood DJ, Chapman KT. Berk SC, et al. Among authors: mosley rt. J Comb Chem. 1999 Sep-Oct;1(5):388-96. doi: 10.1021/cc990017h. J Comb Chem. 1999. PMID: 10748735

4

Spiro[1H-indene-1,4'-piperidine] derivatives as potent and selective non-peptide human somatostatin receptor subtype 2 (sst2) agonists.

Yang L, Guo L, Pasternak A, Mosley R, Rohrer S, Birzin E, Foor F, Cheng K, Schaeffer J, Patchett AA. Yang L, et al. J Med Chem. 1998 Jun 18;41(13):2175-9. doi: 10.1021/jm980194h. J Med Chem. 1998. PMID: 9632348 No abstract available.

5

Potent, orally bioavailable somatostatin agonists: good absorption achieved by urea backbone cyclization.

Pasternak A, Pan Y, Marino D, Sanderson PE, Mosley R, Rohrer SP, Birzin ET, Huskey SE, Jacks T, Schleim KD, Cheng K, Schaeffer JM, Patchett AA, Yang L. Pasternak A, et al. Bioorg Med Chem Lett. 1999 Feb 8;9(3):491-6. doi: 10.1016/s0960-894x(99)00016-5. Bioorg Med Chem Lett. 1999. PMID: 10091708

6

6H-Benzo[c]chromen-6-one derivatives as selective ERbeta agonists.

Sun W, Cama LD, Birzin ET, Warrier S, Locco L, Mosley R, Hammond ML, Rohrer SP. Sun W, et al. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1468-72. doi: 10.1016/j.bmcl.2005.12.057. Epub 2006 Jan 18. Bioorg Med Chem Lett. 2006. PMID: 16412638

7

2-Phenylspiroindenes: a novel class of selective estrogen receptor modulators (SERMs).

Blizzard TA, Morgan JD 2nd, Mosley RT, Birzin ET, Frisch K, Rohrer SP, Hammond ML. Blizzard TA, et al. Among authors: mosley rt. Bioorg Med Chem Lett. 2003 Feb 10;13(3):479-83. doi: 10.1016/s0960-894x(02)00985-x. Bioorg Med Chem Lett. 2003. PMID: 12565955

8

Estrogen receptor ligands. Part 1: The discovery of flavanoids with subtype selectivity.

Chen HY, Dykstra KD, Birzin ET, Frisch K, Chan W, Yang YT, Mosley RT, DiNinno F, Rohrer SP, Schaeffer JM, Hammond ML. Chen HY, et al. Among authors: mosley rt. Bioorg Med Chem Lett. 2004 Mar 22;14(6):1417-21. doi: 10.1016/j.bmcl.2004.01.031. Bioorg Med Chem Lett. 2004. PMID: 15006374

9

Estrogen receptor ligands. II. Discovery of benzoxathiins as potent, selective estrogen receptor alpha modulators.

Kim S, Wu JY, Birzin ET, Frisch K, Chan W, Pai LY, Yang YT, Mosley RT, Fitzgerald PM, Sharma N, Dahllund J, Thorsell AG, DiNinno F, Rohrer SP, Schaeffer JM, Hammond ML. Kim S, et al. Among authors: mosley rt. J Med Chem. 2004 Apr 22;47(9):2171-5. doi: 10.1021/jm034243o. J Med Chem. 2004. PMID: 15084115

10

Estrogen receptor ligands. Part 11: Synthesis and activity of isochromans and isothiochromans.

Liu J, Birzin ET, Chan W, Yang YT, Pai LY, Dasilva C, Hayes EC, Mosley RT, Dininno F, Rohrer SP, Schaeffer JM, Hammond ML. Liu J, et al. Among authors: mosley rt. Bioorg Med Chem Lett. 2005 Feb 1;15(3):715-8. doi: 10.1016/j.bmcl.2004.11.018. Bioorg Med Chem Lett. 2005. PMID: 15664843

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