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DNA repair and transcription in human premature aging disorders.
Bohr VA, Dianov G, Balajee A, May A, Orren DK. Bohr VA, et al. Among authors: may a. J Investig Dermatol Symp Proc. 1998 Aug;3(1):11-3. J Investig Dermatol Symp Proc. 1998. PMID: 9732050 Free article. Review.
Helicases are involved in a number of DNA metabolic transactions, including transcription, replication, and DNA repair. Cockayne cells are deficient in a special type of DNA repair, transcription coupled DNA repair, but they also appear to be defective in basal tran …
Helicases are involved in a number of DNA metabolic transactions, including transcription, replication, and DNA repair. Cockayne cell …
Gene expression profiling in Werner syndrome closely resembles that of normal aging.
Kyng KJ, May A, Kølvraa S, Bohr VA. Kyng KJ, et al. Among authors: may a. Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12259-64. doi: 10.1073/pnas.2130723100. Epub 2003 Oct 3. Proc Natl Acad Sci U S A. 2003. PMID: 14527998 Free PMC article.
Werner syndrome (WS) is a premature aging disorder, displaying defects in DNA replication, recombination, repair, and transcription. It has been hypothesized that several WS phenotypes are secondary consequences of aberrant gene expression and that a transcription d …
Werner syndrome (WS) is a premature aging disorder, displaying defects in DNA replication, recombination, repair, and transcription. …
Gene expression responses to DNA damage are altered in human aging and in Werner Syndrome.
Kyng KJ, May A, Stevnsner T, Becker KG, Kølvrå S, Bohr VA. Kyng KJ, et al. Among authors: may a. Oncogene. 2005 Jul 28;24(32):5026-42. doi: 10.1038/sj.onc.1208692. Oncogene. 2005. PMID: 15897889
We examined transcription in cells from young and old individuals and from patients with Werner syndrome (WS), a segmental progeroid condition with a high incidence of cancer, and found various age-associated transcriptional changes depending upon the type of cellul …
We examined transcription in cells from young and old individuals and from patients with Werner syndrome (WS), a segmental progeroid …
Reduced RNA polymerase II transcription in intact and permeabilized Cockayne syndrome group B cells.
Balajee AS, May A, Dianov GL, Friedberg EC, Bohr VA. Balajee AS, et al. Among authors: may a. Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4306-11. doi: 10.1073/pnas.94.9.4306. Proc Natl Acad Sci U S A. 1997. PMID: 9113985 Free PMC article.
Uridine pulse labeling in intact CS-B fibroblasts and lymphoblasts shows a reduction of approximately 50% compared with various normal cells and with cells from a patient with xeroderma pigmentosum (XP) group A. ...The reduced transcription in CS-B cells is c …
Uridine pulse labeling in intact CS-B fibroblasts and lymphoblasts shows a reduction of approximately 50% compared with various norma …
DNA repair of pyrimidine dimers and 6-4 photoproducts in the ribosomal DNA.
Balajee AS, May A, Bohr VA. Balajee AS, et al. Among authors: may a. Nucleic Acids Res. 1999 Jun 15;27(12):2511-20. doi: 10.1093/nar/27.12.2511. Nucleic Acids Res. 1999. PMID: 10352180 Free PMC article.
The nucleolus is a unique structural component of interphase nuclei where the ribosomal genes, trans-cribed by RNA polymerase I (RNA pol I), are organized. ...Immunological staining indicated that various NER proteins, including TFIIH (subunits p62 and p89), p53, Gadd 45 a …
The nucleolus is a unique structural component of interphase nuclei where the ribosomal genes, trans-cribed by RNA polymerase I (RNA …
The Werner syndrome protein is involved in RNA polymerase II transcription.
Balajee AS, Machwe A, May A, Gray MD, Oshima J, Martin GM, Nehlin JO, Brosh R, Orren DK, Bohr VA. Balajee AS, et al. Among authors: may a. Mol Biol Cell. 1999 Aug;10(8):2655-68. doi: 10.1091/mbc.10.8.2655. Mol Biol Cell. 1999. PMID: 10436020 Free PMC article.
Werner syndrome (WS) is a human progeroid syndrome characterized by the early onset of a large number of clinical features associated with the normal aging process. ...A deficit in either global or regional transcription in WS cells may be a pri …
Werner syndrome (WS) is a human progeroid syndrome characterized by the early onset of a large number of clinical features ass …
2,534 results