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Distinct mechanism for antidepressant activity by blockade of central substance P receptors.
Kramer MS, Cutler N, Feighner J, Shrivastava R, Carman J, Sramek JJ, Reines SA, Liu G, Snavely D, Wyatt-Knowles E, Hale JJ, Mills SG, MacCoss M, Swain CJ, Harrison T, Hill RG, Hefti F, Scolnick EM, Cascieri MA, Chicchi GG, Sadowski S, Williams AR, Hewson L, Smith D, Carlson EJ, Hargreaves RJ, Rupniak NM. Kramer MS, et al. Among authors: hewson l. Science. 1998 Sep 11;281(5383):1640-5. doi: 10.1126/science.281.5383.1640. Science. 1998. PMID: 9733503 Clinical Trial.
Substance P (neurokinin 1) receptor antagonists enhance dorsal raphe neuronal activity.
Conley RK, Cumberbatch MJ, Mason GS, Williamson DJ, Harrison T, Locker K, Swain C, Maubach K, O'Donnell R, Rigby M, Hewson L, Smith D, Rupniak NM. Conley RK, et al. Among authors: hewson l. J Neurosci. 2002 Sep 1;22(17):7730-6. doi: 10.1523/JNEUROSCI.22-17-07730.2002. J Neurosci. 2002. PMID: 12196596 Free PMC article.
Edg2 receptor distribution in adult rat brain.
Handford EJ, Smith D, Hewson L, McAllister G, Beer MS. Handford EJ, et al. Among authors: hewson l. Neuroreport. 2001 Mar 26;12(4):757-60. doi: 10.1097/00001756-200103260-00029. Neuroreport. 2001. PMID: 11277579
Molecular and functional diversity of the expanding GABA-A receptor gene family.
Whiting PJ, Bonnert TP, McKernan RM, Farrar S, Le Bourdellès B, Heavens RP, Smith DW, Hewson L, Rigby MR, Sirinathsinghji DJ, Thompson SA, Wafford KA. Whiting PJ, et al. Among authors: hewson l. Ann N Y Acad Sci. 1999 Apr 30;868:645-53. doi: 10.1111/j.1749-6632.1999.tb11341.x. Ann N Y Acad Sci. 1999. PMID: 10414349 Review.
theta, a novel gamma-aminobutyric acid type A receptor subunit.
Bonnert TP, McKernan RM, Farrar S, le Bourdellès B, Heavens RP, Smith DW, Hewson L, Rigby MR, Sirinathsinghji DJ, Brown N, Wafford KA, Whiting PJ. Bonnert TP, et al. Among authors: hewson l. Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9891-6. doi: 10.1073/pnas.96.17.9891. Proc Natl Acad Sci U S A. 1999. PMID: 10449790 Free PMC article.
33 results