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ShK-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide.
J Biol Chem. 1998 Dec 4;273(49):32697-707. doi: 10.1074/jbc.273.49.32697.
J Biol Chem. 1998.
PMID: 9830012
Free article.
Structure-guided transformation of charybdotoxin yields an analog that selectively targets Ca(2+)-activated over voltage-gated K(+) channels.
Rauer H, Lanigan MD, Pennington MW, Aiyar J, Ghanshani S, Cahalan MD, Norton RS, Chandy KG.
Rauer H, et al. Among authors: lanigan md.
J Biol Chem. 2000 Jan 14;275(2):1201-8. doi: 10.1074/jbc.275.2.1201.
J Biol Chem. 2000.
PMID: 10625664
Free article.
Item in Clipboard
Mutating a critical lysine in ShK toxin alters its binding configuration in the pore-vestibule region of the voltage-gated potassium channel, Kv1.3.
Lanigan MD, Kalman K, Lefievre Y, Pennington MW, Chandy KG, Norton RS.
Lanigan MD, et al.
Biochemistry. 2002 Oct 8;41(40):11963-71. doi: 10.1021/bi026400b.
Biochemistry. 2002.
PMID: 12356296
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Role of disulfide bonds in the structure and potassium channel blocking activity of ShK toxin.
Pennington MW, Lanigan MD, Kalman K, Mahnir VM, Rauer H, McVaugh CT, Behm D, Donaldson D, Chandy KG, Kem WR, Norton RS.
Pennington MW, et al. Among authors: lanigan md.
Biochemistry. 1999 Nov 2;38(44):14549-58. doi: 10.1021/bi991282m.
Biochemistry. 1999.
PMID: 10545177
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A helical capping motif in ShK toxin and its role in helix stabilization.
Lanigan MD, Tudor JE, Pennington MW, Norton RS.
Lanigan MD, et al.
Biopolymers. 2001 Apr 5;58(4):422-36. doi: 10.1002/1097-0282(20010405)58:4<422::AID-BIP1018>3.0.CO;2-T.
Biopolymers. 2001.
PMID: 11180055
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Designed peptide analogues of the potassium channel blocker ShK toxin.
Lanigan MD, Pennington MW, Lefievre Y, Rauer H, Norton RS.
Lanigan MD, et al.
Biochemistry. 2001 Dec 25;40(51):15528-37. doi: 10.1021/bi011300b.
Biochemistry. 2001.
PMID: 11747428
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Mycobacterial proteome extraction: comparison of disruption methods.
Lanigan MD, Vaughan JA, Shiell BJ, Beddome GJ, Michalski WP.
Lanigan MD, et al.
Proteomics. 2004 Apr;4(4):1094-100. doi: 10.1002/pmic.200300672.
Proteomics. 2004.
PMID: 15048990
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The recovery of Mycobacterium avium subspecies paratuberculosis from the intestine of infected ruminants for proteomic evaluation.
Egan S, Lanigan M, Shiell B, Beddome G, Stewart D, Vaughan J, Michalski WP.
Egan S, et al.
J Microbiol Methods. 2008 Sep;75(1):29-39. doi: 10.1016/j.mimet.2008.04.008. Epub 2008 May 14.
J Microbiol Methods. 2008.
PMID: 18547663
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