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Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia.
Membrez M, Migliavacca E, Christen S, Yaku K, Trieu J, Lee AK, Morandini F, Giner MP, Stiner J, Makarov MV, Garratt ES, Vasiloglou MF, Chanvillard L, Dalbram E, Ehrlich AM, Sanchez-Garcia JL, Canto C, Karagounis LG, Treebak JT, Migaud ME, Heshmat R, Razi F, Karnani N, Ostovar A, Farzadfar F, Tay SKH, Sanders MJ, Lillycrop KA, Godfrey KM, Nakagawa T, Moco S, Koopman R, Lynch GS, Sorrentino V, Feige JN. Membrez M, et al. Among authors: migaud me. Nat Metab. 2024 Mar;6(3):433-447. doi: 10.1038/s42255-024-00997-x. Epub 2024 Mar 19. Nat Metab. 2024. PMID: 38504132 Free PMC article.
Discovery of fungal surface NADases predominantly present in pathogenic species.
Strømland Ø, Kallio JP, Pschibul A, Skoge RH, Harðardóttir HM, Sverkeli LJ, Heinekamp T, Kniemeyer O, Migaud M, Makarov MV, Gossmann TI, Brakhage AA, Ziegler M. Strømland Ø, et al. Among authors: migaud m. Nat Commun. 2021 Mar 12;12(1):1631. doi: 10.1038/s41467-021-21307-z. Nat Commun. 2021. PMID: 33712585 Free PMC article.
Scalable syntheses of traceable ribosylated NAD+ precursors.
Makarov MV, Harris NW, Rodrigues M, Migaud ME. Makarov MV, et al. Among authors: migaud me. Org Biomol Chem. 2019 Oct 14;17(38):8716-8720. doi: 10.1039/c9ob01981b. Epub 2019 Sep 20. Org Biomol Chem. 2019. PMID: 31538639 Free PMC article.
SLC25A51 is a mammalian mitochondrial NAD+ transporter.
Luongo TS, Eller JM, Lu MJ, Niere M, Raith F, Perry C, Bornstein MR, Oliphint P, Wang L, McReynolds MR, Migaud ME, Rabinowitz JD, Johnson FB, Johnsson K, Ziegler M, Cambronne XA, Baur JA. Luongo TS, et al. Among authors: migaud me. Nature. 2020 Dec;588(7836):174-179. doi: 10.1038/s41586-020-2741-7. Epub 2020 Sep 9. Nature. 2020. PMID: 32906142 Free PMC article.
Novel synthetic route to the C-nucleoside, 2-deoxy benzamide riboside.
Midtkandal RR, Redpath P, Trammell SA, Macdonald SJ, Brenner C, Migaud ME. Midtkandal RR, et al. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5204-7. doi: 10.1016/j.bmcl.2012.06.069. Epub 2012 Jun 28. Bioorg Med Chem Lett. 2012. PMID: 22795628 Free PMC article.
224 results