Wang PR - Search Results

1

3-Pyridylethanolamines: potent and selective human beta 3 adrenergic receptor agonists.

Naylor EM, Colandrea VJ, Candelore MR, Cascieri MA, Colwell LF Jr, Deng L, Feeney WP, Forrest MJ, Hom GJ, MacIntyre DE, Strader CD, Tota L, Wang PR, Wyvratt MJ, Fisher MH, Weber AE. Naylor EM, et al. Among authors: wang pr. Bioorg Med Chem Lett. 1998 Nov 3;8(21):3087-92. doi: 10.1016/s0960-894x(98)00571-x. Bioorg Med Chem Lett. 1998. PMID: 9873681

2

Substituted oxazole benzenesulfonamides as potent human beta3 adrenergic receptor agonists.

Ok HO, Reigle LB, Candelore MR, Cascieri MA, Colwell LF, Deng L, Feeney WP, Forrest MJ, Hom GJ, MacIntyre DE, Strader CD, Tota L, Wang P, Wyvratt MJ, Fisher MH, Weber AE. Ok HO, et al. Bioorg Med Chem Lett. 2000 Jul 17;10(14):1531-4. doi: 10.1016/s0960-894x(00)00277-8. Bioorg Med Chem Lett. 2000. PMID: 10915043

3

Human beta3 adrenergic receptor agonists containing imidazolidinone and imidazolone benzenesulfonamides.

Naylor EM, Parmee ER, Colandrea VJ, Perkins L, Brockunier L, Candelore MR, Cascieri MA, Colwell LF Jr, Deng L, Feeney WP, Forrest MJ, Hom GJ, MacIntyre DE, Strader CD, Tota L, Wang PR, Wyvratt MJ, Fisher MH, Weber AE. Naylor EM, et al. Among authors: wang pr. Bioorg Med Chem Lett. 1999 Mar 8;9(5):755-8. doi: 10.1016/s0960-894x(99)00072-4. Bioorg Med Chem Lett. 1999. PMID: 10201842

4

Design and synthesis of alpha-aryloxyphenylacetic acid derivatives: a novel class of PPARalpha/gamma dual agonists with potent antihyperglycemic and lipid modulating activity.

Shi GQ, Dropinski JF, McKeever BM, Xu S, Becker JW, Berger JP, MacNaul KL, Elbrecht A, Zhou G, Doebber TW, Wang P, Chao YS, Forrest M, Heck JV, Moller DE, Jones AB. Shi GQ, et al. J Med Chem. 2005 Jun 30;48(13):4457-68. doi: 10.1021/jm0502135. J Med Chem. 2005. PMID: 15974597

5

Comparison of Cardiovascular Parameters and/or Serum Chemistry and Hematology Profiles in Conscious and Anesthetized Rhesus Monkeys (Macaca mulatta).

Hom GJ, Bach TJ, Carroll D, Forrest MJ, Mariano MA, Trainor CE, Wang PR, MacIntyre DE. Hom GJ, et al. Among authors: wang pr. Contemp Top Lab Anim Sci. 1999 Mar;38(2):60-64. Contemp Top Lab Anim Sci. 1999. PMID: 12086436

6

Rapid pharmacokinetic screening for the selection of new drug discovery candidates using a generic isocratic liquid chromatography--atmospheric pressure ionization tandem mass spectrometry method.

Colwell LF Jr, Tamvakopoulos CS, Wang PR, Pivnichny JV, Shih TL. Colwell LF Jr, et al. Among authors: wang pr. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 May 25;772(1):89-98. doi: 10.1016/s1570-0232(02)00061-2. J Chromatogr B Analyt Technol Biomed Life Sci. 2002. PMID: 12016019

7

(2R)-2-methylchromane-2-carboxylic acids: discovery of selective PPARalpha agonists as hypolipidemic agents.

Koyama H, Boueres JK, Miller DJ, Berger JP, MacNaul KL, Wang PR, Ippolito MC, Wright SD, Agrawal AK, Moller DE, Sahoo SP. Koyama H, et al. Among authors: wang pr. Bioorg Med Chem Lett. 2005 Jul 15;15(14):3347-51. doi: 10.1016/j.bmcl.2005.05.028. Bioorg Med Chem Lett. 2005. PMID: 15950464

8

(2R)-2-ethylchromane-2-carboxylic acids: discovery of novel PPARalpha/gamma dual agonists as antihyperglycemic and hypolipidemic agents.

Koyama H, Miller DJ, Boueres JK, Desai RC, Jones AB, Berger JP, MacNaul KL, Kelly LJ, Doebber TW, Wu MS, Zhou G, Wang PR, Ippolito MC, Chao YS, Agrawal AK, Franklin R, Heck JV, Wright SD, Moller DE, Sahoo SP. Koyama H, et al. Among authors: wang pr. J Med Chem. 2004 Jun 3;47(12):3255-63. doi: 10.1021/jm030621d. J Med Chem. 2004. PMID: 15163205

9

MK-0767, a novel dual PPARalpha/gamma agonist, displays robust antihyperglycemic and hypolipidemic activities.

Doebber TW, Kelly LJ, Zhou G, Meurer R, Biswas C, Li Y, Wu MS, Ippolito MC, Chao YS, Wang PR, Wright SD, Moller DE, Berger JP. Doebber TW, et al. Among authors: wang pr. Biochem Biophys Res Commun. 2004 May 28;318(2):323-8. doi: 10.1016/j.bbrc.2004.04.032. Biochem Biophys Res Commun. 2004. PMID: 15120604

10

High fat fed hamster, a unique animal model for treatment of diabetic dyslipidemia with peroxisome proliferator activated receptor alpha selective agonists.

Wang PR, Guo Q, Ippolito M, Wu M, Milot D, Ventre J, Doebber T, Wright SD, Chao YS. Wang PR, et al. Eur J Pharmacol. 2001 Sep 21;427(3):285-93. doi: 10.1016/s0014-2999(01)01249-3. Eur J Pharmacol. 2001. PMID: 11567659

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