Mosley RT - Search Results

1

Molecular interaction of Agouti protein and Agouti-related protein with human melanocortin receptors.

Tota MR, Smith TS, Mao C, MacNeil T, Mosley RT, Van der Ploeg LH, Fong TM. Tota MR, et al. Among authors: mosley rt. Biochemistry. 1999 Jan 19;38(3):897-904. doi: 10.1021/bi9815602. Biochemistry. 1999. PMID: 9893984

2

Molecular determinants of ligand binding to the human melanocortin-4 receptor.

Yang YK, Fong TM, Dickinson CJ, Mao C, Li JY, Tota MR, Mosley R, Van Der Ploeg LH, Gantz I. Yang YK, et al. Biochemistry. 2000 Dec 5;39(48):14900-11. doi: 10.1021/bi001684q. Biochemistry. 2000. PMID: 11101306

3

Structure-activity relationship of linear tetrapeptides Tic-DPhe-Arg-Trp-NH2 at the human melanocortin-4 receptor and effects on feeding behaviors in rat.

Ye Z, MacNeil T, Weinberg DH, Kalyani RN, Tang R, Strack AM, Murphy BA, Mosley RT, Euan MacIntyre D, Van der Ploeg LH, Patchett AA, Wyvratt MJ, Nargund RP. Ye Z, et al. Among authors: mosley rt. Peptides. 2005 Oct;26(10):2017-25. doi: 10.1016/j.peptides.2004.12.035. Peptides. 2005. PMID: 15993513

4

Design and pharmacology of N-[(3R)-1,2,3,4-tetrahydroisoquinolinium- 3-ylcarbonyl]-(1R)-1-(4-chlorobenzyl)- 2-[4-cyclohexyl-4-(1H-1,2,4-triazol- 1-ylmethyl)piperidin-1-yl]-2-oxoethylamine (1), a potent, selective, melanocortin subtype-4 receptor agonist.

Sebhat IK, Martin WJ, Ye Z, Barakat K, Mosley RT, Johnston DB, Bakshi R, Palucki B, Weinberg DH, MacNeil T, Kalyani RN, Tang R, Stearns RA, Miller RR, Tamvakopoulos C, Strack AM, McGowan E, Cashen DE, Drisko JE, Hom GJ, Howard AD, MacIntyre DE, van der Ploeg LH, Patchett AA, Nargund RP. Sebhat IK, et al. Among authors: mosley rt. J Med Chem. 2002 Oct 10;45(21):4589-93. doi: 10.1021/jm025539h. J Med Chem. 2002. PMID: 12361385

5

1H-NMR studies on a potent and selective antagonist at human melanocortin receptor 4 (hMC-4R).

Victoria Silva Elipe M, Mosley RT, Bednarek MA, Arison BH. Victoria Silva Elipe M, et al. Among authors: mosley rt. Biopolymers. 2003 Apr;68(4):512-27. doi: 10.1002/bip.10340. Biopolymers. 2003. PMID: 12666176

6

Selective glucocorticoid receptor nonsteroidal ligands completely antagonize the dexamethasone mediated induction of enzymes involved in gluconeogenesis and glutamine metabolism.

Einstein M, Greenlee M, Rouen G, Sitlani A, Santoro J, Wang C, Pandit S, Mazur P, Smalera I, Weaver AP, Zeng YY, Ge L, Kelly T, Paiva T, Geissler W, Mosley RT, Williamson J, Ali A, Balkovec J, Harris G. Einstein M, et al. Among authors: mosley rt. J Steroid Biochem Mol Biol. 2004 Dec;92(5):345-56. doi: 10.1016/j.jsbmb.2004.10.009. Epub 2005 Jan 21. J Steroid Biochem Mol Biol. 2004. PMID: 15698539

7

Estrogen receptor ligands. Part 16: 2-Aryl indoles as highly subtype selective ligands for ERalpha.

Dykstra KD, Guo L, Birzin ET, Chan W, Yang YT, Hayes EC, DaSilva CA, Pai LY, Mosley RT, Kraker B, Fitzgerald PM, DiNinno F, Rohrer SP, Schaeffer JM, Hammond ML. Dykstra KD, et al. Among authors: mosley rt. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2322-8. doi: 10.1016/j.bmcl.2007.01.054. Epub 2007 Jan 25. Bioorg Med Chem Lett. 2007. PMID: 17289385

8

Structure and chemistry of apicidins, a class of novel cyclic tetrapeptides without a terminal alpha-keto epoxide as inhibitors of histone deacetylase with potent antiprotozoal activities.

Singh SB, Zink DL, Liesch JM, Mosley RT, Dombrowski AW, Bills GF, Darkin-Rattray SJ, Schmatz DM, Goetz MA. Singh SB, et al. Among authors: mosley rt. J Org Chem. 2002 Feb 8;67(3):815-25. doi: 10.1021/jo016088w. J Org Chem. 2002. PMID: 11856024

9

Identification of Leu276 of the S1P1 receptor and Phe263 of the S1P3 receptor in interaction with receptor specific agonists by molecular modeling, site-directed mutagenesis, and affinity studies.

Deng Q, Clemas JA, Chrebet G, Fischer P, Hale JJ, Li Z, Mills SG, Bergstrom J, Mandala S, Mosley R, Parent SA. Deng Q, et al. Mol Pharmacol. 2007 Mar;71(3):724-35. doi: 10.1124/mol.106.029223. Epub 2006 Dec 14. Mol Pharmacol. 2007. PMID: 17170199

10

Amino acid substitution of arginine 80 in 17beta-hydroxysteroid dehydrogenase type 3 and its effect on NADPH cofactor binding and oxidation/reduction kinetics.

McKeever BM, Hawkins BK, Geissler WM, Wu L, Sheridan RP, Mosley RT, Andersson S. McKeever BM, et al. Among authors: mosley rt. Biochim Biophys Acta. 2002 Nov 19;1601(1):29-37. doi: 10.1016/s1570-9639(02)00434-x. Biochim Biophys Acta. 2002. PMID: 12429500

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