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Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active rheumatoid arthritis: a double-blind, randomised, multicentre trial. European Leflunomide Study Group.
Smolen JS, Kalden JR, Scott DL, Rozman B, Kvien TK, Larsen A, Loew-Friedrich I, Oed C, Rosenburg R. Smolen JS, et al. Among authors: loew friedrich i. Lancet. 1999 Jan 23;353(9149):259-66. doi: 10.1016/s0140-6736(98)09403-3. Lancet. 1999. PMID: 9929017 Clinical Trial.
Treatment of active rheumatoid arthritis with leflunomide: two year follow up of a double blind, placebo controlled trial versus sulfasalazine.
Scott DL, Smolen JS, Kalden JR, van de Putte LB, Larsen A, Kvien TK, Schattenkirchner M, Nash P, Oed C, Loew-Friedrich I; European Leflunomide Study Group. Scott DL, et al. Among authors: loew friedrich i. Ann Rheum Dis. 2001 Oct;60(10):913-23. doi: 10.1136/ard.60.10.913. Ann Rheum Dis. 2001. PMID: 11557646 Free PMC article. Clinical Trial.
A comparison of the efficacy and safety of leflunomide and methotrexate for the treatment of rheumatoid arthritis.
Emery P, Breedveld FC, Lemmel EM, Kaltwasser JP, Dawes PT, Gömör B, Van Den Bosch F, Nordström D, Bjorneboe O, Dahl R, Horslev-Petersen K, Rodriguez De La Serna A, Molloy M, Tikly M, Oed C, Rosenburg R, Loew-Friedrich I. Emery P, et al. Among authors: loew friedrich i. Rheumatology (Oxford). 2000 Jun;39(6):655-65. doi: 10.1093/rheumatology/39.6.655. Rheumatology (Oxford). 2000. PMID: 10888712 Clinical Trial.
Treatment with leflunomide slows radiographic progression of rheumatoid arthritis: results from three randomized controlled trials of leflunomide in patients with active rheumatoid arthritis. Leflunomide Rheumatoid Arthritis Investigators Group.
Sharp JT, Strand V, Leung H, Hurley F, Loew-Friedrich I. Sharp JT, et al. Among authors: loew friedrich i. Arthritis Rheum. 2000 Mar;43(3):495-505. doi: 10.1002/1529-0131(200003)43:3<495::AID-ANR4>3.0.CO;2-U. Arthritis Rheum. 2000. PMID: 10728741 Free article. Clinical Trial.
Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate. Leflunomide Rheumatoid Arthritis Investigators Group.
Strand V, Cohen S, Schiff M, Weaver A, Fleischmann R, Cannon G, Fox R, Moreland L, Olsen N, Furst D, Caldwell J, Kaine J, Sharp J, Hurley F, Loew-Friedrich I. Strand V, et al. Among authors: loew friedrich i. Arch Intern Med. 1999 Nov 22;159(21):2542-50. doi: 10.1001/archinte.159.21.2542. Arch Intern Med. 1999. PMID: 10573044 Clinical Trial.